Assembly of nucleobases into rings and cages via metal ions

Lippert, Bernhard ; Sanz Miguel, Pablo J. (Universidad de Zaragoza)

Resumen: Metal ions are natural counterparts of nucleic acids and crucial in stabilizing many specific structures. While the relevant bulk main group metal ions (Na+, K+, Mg2+) are predominantly important in keeping base pairs in register and/or allowing the formation of particular specific RNA structures, transition metal ions, and specifically the soft ones, display a pronounced affinity for donor atoms of the heterocyclic nucleobases as part of nucleic acids. Their nature in fact provides a large number of different binding patterns, including specific cross-links and/or the formation of cyclic entities and/or cages. This review article summarizes constructs obtained this way, without over-emphasizing their biological relevance. Nevertheless, it can be claimed that in a number of cases model findings have preceded their discoveries in biorelevant events.

Idioma: Inglés

DOI: 10.1080/00958972.2022.2105144

Año: 2022

Publicado en: Journal of Coordination Chemistry 75, 17-18 (2022), [26 pp.]
ISSN: 0095-8972

Factor impacto JCR: 1.9 (2022)

Categ. JCR: CHEMISTRY, INORGANIC & NUCLEAR rank: 26 / 42 = 0.619 (2022) - Q3 - T2

Factor impacto CITESCORE: 3.0 - Chemistry (Q3) - Materials Science (Q3)

Factor impacto SCIMAGO: 0.279 - Physical and Theoretical Chemistry (Q3) - Materials Chemistry (Q3)

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Química Inorgánica (Dpto. Química Inorgánica)