000150547 001__ 150547
000150547 005__ 20251017144646.0
000150547 0247_ $$2doi$$a10.1016/j.numecd.2024.103811
000150547 0248_ $$2sideral$$a142607
000150547 037__ $$aART-2024-142607
000150547 041__ $$aeng
000150547 100__ $$aSkapino, Estela
000150547 245__ $$aIndependent effect of body fat content on inflammatory biomarkers in children and adolescents: The GENOBOX study
000150547 260__ $$c2024
000150547 5060_ $$aAccess copy available to the general public$$fUnrestricted
000150547 5203_ $$aBackground and aims: To assess the relationship between body composition indicators and inflammatory bio-markers in children and adolescents of the GENOBOX study.
Methods and results: Anthropometry data from 264 subjects from the subsample of Zaragoza (Spain) included: weight, height, waist circumference, body mass index and triponderal index. Body composition was determined by Dual-energy X-ray Absorptiometry (DXA), obtaining visceral adipose tissue, fat mass index and lean mass index. Age and sex specific z-scores were computed. Simple linear regression models were performed with in-flammatory biomarkers (hsCRP, IL8, TNF-α, adiponectin, leptin and resistin) as dependent variables, and each of the body composition indices as independent variables.
Prepubertal boys had higher IL8 and resistin values and pubertal girls had higher HOMA-IR and leptin values. hsCPR and leptin were associated with fat mass, both in prepubertals and pubertals, independently of lean mass, and regardless of how body composition was measured. All body composition indices were inversely associated with adiponectin, except for fat mass index in pubertals, but none of them were statistically significant. Conclusion: A positive association between hsCRP and leptin with all body fat composition parameters, measured by standard nutritional indicators and DXA, was observed in both sexual stages.
000150547 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI051968$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-01425$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02042$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02059$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-00871$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-01205$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-01301$$9info:eu-repo/grantAgreement/ES/ISCIII/RETICS-RD12-0026-0015$$9info:eu-repo/grantAgreement/ES/MEC/FPU16-03653$$9info:eu-repo/grantAgreement/ES/MICIN-ISCIII/IFI17-00048
000150547 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000150547 590__ $$a3.7$$b2024
000150547 592__ $$a1.098$$b2024
000150547 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b55 / 230 = 0.239$$c2024$$dQ1$$eT1
000150547 593__ $$aCardiology and Cardiovascular Medicine$$c2024$$dQ1
000150547 591__ $$aNUTRITION & DIETETICS$$b39 / 112 = 0.348$$c2024$$dQ2$$eT2
000150547 593__ $$aNutrition and Dietetics$$c2024$$dQ1
000150547 591__ $$aENDOCRINOLOGY & METABOLISM$$b63 / 191 = 0.33$$c2024$$dQ2$$eT1
000150547 593__ $$aMedicine (miscellaneous)$$c2024$$dQ1
000150547 593__ $$aEndocrinology, Diabetes and Metabolism$$c2024$$dQ2
000150547 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000150547 700__ $$aGonzalez-Gayan, Laura
000150547 700__ $$0(orcid)0000-0001-6899-5938$$aSeral-Cortes, Miguel$$uUniversidad de Zaragoza
000150547 700__ $$aSabroso-Lasa, Sergio
000150547 700__ $$aLlorente-Cereza, Ma Teresa$$uUniversidad de Zaragoza
000150547 700__ $$aLeis, Rosaura
000150547 700__ $$aAguilera, Concepción M.
000150547 700__ $$aGil-Campos, Mercedes
000150547 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis A.$$uUniversidad de Zaragoza
000150547 700__ $$0(orcid)0000-0002-0902-387X$$aBueno-Lozano, Gloria$$uUniversidad de Zaragoza
000150547 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000150547 7102_ $$11011$$2670$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Pediatría
000150547 773__ $$g35, 4 (2024), 103811 [8 pp.]$$pNMCD, Nutr. Metab. Cardiovasc. Dis.$$tNutrition, Metabolism and Cardiovascular Diseases$$x0939-4753
000150547 8564_ $$s961270$$uhttps://zaguan.unizar.es/record/150547/files/texto_completo.pdf$$yVersión publicada
000150547 8564_ $$s2508165$$uhttps://zaguan.unizar.es/record/150547/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000150547 909CO $$ooai:zaguan.unizar.es:150547$$particulos$$pdriver
000150547 951__ $$a2025-10-17-14:34:27
000150547 980__ $$aARTICLE