Assessment of Material Properties in Key Components of the Porcine Crystalline Lens During Overshooting
Salimibani, Milad ; Dahaghin, Ali ; Boszczyk, Agnieszka ; Grasa, Jorge (Universidad de Zaragoza) ; Siedlecki, Damian
Resumen: Purpose: The porcine eye serves as a valuable surrogate for studying human ocular anatomy and physiology because of its close resemblance. This study focuses on the influence of material properties, specifically Young’s modulus and Poisson’s ratio, on the crystalline lens overshooting amplitude during rapid eye rotation.
Methods:The Finite Element Method (FEM) is employed to explore various material property scenarios, and sensitivity analysis is conducted to assess their impact on the mechanical displacement of the crystalline lens apex. The measurements were made of three output parameters: maximum displacement, time of maximum displacement appearance , and stabilization time.
Results:The results highlight the significance of fine-tuning of the zonule’s material properties, particularly Young’s modulus, in achieving a reliable model. They suggest that fine-tuning of these parameters can lead to a highly reliable model, enabling in-depth research in the opto-dynamic simulations.
Conclusions: Having a complete examination of crystalline lens displacement in ex vivo porcine eye models and detailing crucial factors for accurate modeling will open the path for future studies especially in conditions affected by dynamic aspects of the crystalline lens or in in vivo research.
Idioma: Inglés
DOI: 10.37190/abb-02463-2024-03
Año: 2024
Publicado en: ACTA OF BIOENGINEERING AND BIOMECHANICS 26, 4 (2024), [12 pp.]
ISSN: 1509-409X
Factor impacto JCR: 0.8 (2024)
Categ. JCR: ENGINEERING, BIOMEDICAL rank: 111 / 124 = 0.895 (2024) - Q4 - T3
Categ. JCR: BIOPHYSICS rank: 74 / 79 = 0.937 (2024) - Q4 - T3
Factor impacto CITESCORE: 1.8 - Biophysics (Q4) - Biomaterials (Q4) - Biomedical Engineering (Q4) - Bioengineering (Q4)
Factor impacto SCIMAGO: 0.195 - Bioengineering (Q4) - Biophysics (Q4) - Biomedical Engineering (Q4) - Biomaterials (Q4)
Financiación: info:eu-repo/grantAgreement/EC/H2020/956720/EU/Opto-Biomechanical Eye Research Network/OBERON
Tipo y forma: Article (Published version)
Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
Exportado de SIDERAL (2026-01-12-12:36:43)
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Methods:The Finite Element Method (FEM) is employed to explore various material property scenarios, and sensitivity analysis is conducted to assess their impact on the mechanical displacement of the crystalline lens apex. The measurements were made of three output parameters: maximum displacement, time of maximum displacement appearance , and stabilization time.
Results:The results highlight the significance of fine-tuning of the zonule’s material properties, particularly Young’s modulus, in achieving a reliable model. They suggest that fine-tuning of these parameters can lead to a highly reliable model, enabling in-depth research in the opto-dynamic simulations.
Conclusions: Having a complete examination of crystalline lens displacement in ex vivo porcine eye models and detailing crucial factors for accurate modeling will open the path for future studies especially in conditions affected by dynamic aspects of the crystalline lens or in in vivo research.
Idioma: Inglés
DOI: 10.37190/abb-02463-2024-03
Año: 2024
Publicado en: ACTA OF BIOENGINEERING AND BIOMECHANICS 26, 4 (2024), [12 pp.]
ISSN: 1509-409X
Factor impacto JCR: 0.8 (2024)
Categ. JCR: ENGINEERING, BIOMEDICAL rank: 111 / 124 = 0.895 (2024) - Q4 - T3
Categ. JCR: BIOPHYSICS rank: 74 / 79 = 0.937 (2024) - Q4 - T3
Factor impacto CITESCORE: 1.8 - Biophysics (Q4) - Biomaterials (Q4) - Biomedical Engineering (Q4) - Bioengineering (Q4)
Factor impacto SCIMAGO: 0.195 - Bioengineering (Q4) - Biophysics (Q4) - Biomedical Engineering (Q4) - Biomaterials (Q4)
Financiación: info:eu-repo/grantAgreement/EC/H2020/956720/EU/Opto-Biomechanical Eye Research Network/OBERON
Tipo y forma: Article (Published version)
Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2026-01-12-12:36:43)
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Este artículo se encuentra en las siguientes colecciones:
Articles > Artículos por área > Mec. de Medios Contínuos y Teor. de Estructuras
Record created 2025-04-01, last modified 2026-01-12