Simple iodoalkyne-based organocatalysts for the activation of carbonyl compounds
Alegre-Requena, Juan V. ; Valero-Tena, Alberto ; Giménez Sonsona, Isaac ; Uriel, Santiago (Universidad de Zaragoza) ; Pérez Herrera, Raquel (Universidad de Zaragoza)
Resumen: A novel approach for the formation of bisindolylmethane derivatives (BIMs) is described as a proof of concept to evaluate the catalytic capacity of iodoalkynes. The use of these derivatives is reported as an example of simple halogen bond-based organocatalyst. This kind of activation has not been used before for the synthesis of bisindolylmethane derivatives 3. Interestingly, the preparation of 3-(1H-indol-3-yl)-1-phenylbutan-1-one (8) has been also achieved for the first time with an iodoalkyne derivative. We prove the efficiency of this family of new catalysts by developing a simple and easy operational methodology, opening the door to the development of alternative catalysts in the area of halogen bond-based organocatalysts.
Idioma: Inglés
DOI: 10.1039/c9ob02688f
Año: 2020
Publicado en: Organic & Biomolecular Chemistry 18, 8 (2020), 1594-1601
ISSN: 1477-0520
Factor impacto JCR: 3.876 (2020)
Categ. JCR: CHEMISTRY, ORGANIC rank: 13 / 57 = 0.228 (2020) - Q1 - T1
Factor impacto SCIMAGO: 0.923 - Biochemistry (Q1) - Physical and Theoretical Chemistry (Q1) - Organic Chemistry (Q1)
Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E07-17R
Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E47-17R
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2017-88091-P
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/PGC2018-093761-B-C31
Tipo y forma: Article (Published version)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2025-10-17-14:12:27)
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Idioma: Inglés
DOI: 10.1039/c9ob02688f
Año: 2020
Publicado en: Organic & Biomolecular Chemistry 18, 8 (2020), 1594-1601
ISSN: 1477-0520
Factor impacto JCR: 3.876 (2020)
Categ. JCR: CHEMISTRY, ORGANIC rank: 13 / 57 = 0.228 (2020) - Q1 - T1
Factor impacto SCIMAGO: 0.923 - Biochemistry (Q1) - Physical and Theoretical Chemistry (Q1) - Organic Chemistry (Q1)
Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E07-17R
Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E47-17R
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2017-88091-P
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/PGC2018-093761-B-C31
Tipo y forma: Article (Published version)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2025-10-17-14:12:27)
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Record created 2025-05-16, last modified 2025-10-17