The associations of childhood adversities and mental disorders with suicidal thoughts and behaviors - Results from the World Mental Health International College Student Initiative
Mortier, Philippe ; Yang, Xue ; Altwaijri, Yasmin A. ; Holdcraft, Jacob A. ; Lee, Sue ; Sampson, Nancy A ; Albor, Yesica ; Alhadi, Ahmad N. ; Alonso, Jordi ; Al-Saud, Nouf K. ; Andersson, Claes ; Atwoli, Lukoye ; Auerbach, Randy P. ; Muaka, Caroline Ayuya ; Báez-Mansur, Patricia M. ; Ballester, Laura ; Bantjes, Jason ; Baumeister, Harald ; Bendtsen, Marcus ; Benjet, Corina ; Berman, Anne H. ; Bruffaerts, Ronny ; Carrasco, Paula ; Chan, Silver C.N. ; Cohut, Irina ; Covarrubias Díaz Couder, María Anabell ; Crockett, Marcelo A. ; Cuijpers, Pim ; David, Oana A. ; Dong, Dong ; Ebert, David D. ; Gaete, Jorge ; Felez-Nobrega, Mireia ; García Forero, Carlos ; Gili, Margalida ; Gutiérrez-García, Raúl A. ; Haro, Josep Maria ; Hasking, Penelope ; Hunt, Xanthe ; Husky, Mathilde M. ; Jaguga, Florence ; Jansen, Leontien ; Langer, Álvaro I. ; Liu, Yan ; Mac-Ginty, Scarlett ; Martínez, Vania ; Mason, Andre ; Mathai, Muthoni ; McLafferty, Margaret ; Miranda-Mendizabal, Andrea ; Murray, Elaine K. ; Musyoka, Catherine M. ; O’Neill, Siobhan M. ; Papasteri, Claudiu C. ; Piqueras, José A. ; Popescu, Codruta A. ; Rapsey, Charlene ; Robinson, Kealagh ; Rodriguez-Jimenez, Tiscar (Universidad de Zaragoza) ; Scarf, Damian ; Siu, Oi-ling ; Stein, Dan J. ; Struijs, Sascha Y. ; Tomoiaga, Cristina T. ; Valdés-García, Karla Patricia ; Vereecke, Shelby ; Vigo, Daniel V. ; Wang, Angel Y. ; Wong, Samuel Y.S. ; Kessler, Ronald C.
Resumen: Objective. To investigate the associations of demographic variables, childhood adversities (CAs), and mental disorders (MDx) with onset, transition, and persistence of suicidal thoughts and behaviors (STB) among first-year university students.
Method. Poisson regression models within a discrete-time survival framework were constructed using web-based self-report survey data from 72,288 incoming university students across 18 countries (response rate=20.9%; median age=19 years, 57.9% female, 1.4% transgender, 21.0% non-heterosexual). These models examined the associations of four demographic variables, five CAs, and eight MDx with STB outcomes.
Results. Lifetime prevalence of suicidal ideation, plans, and attempts was 47.0%, 26.0%, and 9.6%, respectively; 12-month estimates were 30.6%, 14.0%, and 2.3%. In unadjusted analyses, associations were strongest between lifetime onset of suicidal ideation and CAs (RR range 4.4–7.0), particularly parental psychopathology (relative risk [RR]=7.0 [95% CI 6.5–7.7]), followed by MDx (RR range 1.3–3.0). Of the demographic subgroups, transgender students had highest risk of STB (lifetime ideation onset RR=2.4 [2.3–2.6]; ideation-to-attempt transition RR=1.5 [1.3–1.8]). In fully adjusted models, strongest predictors of lifetime ideation onset were emotional abuse (RR=2.1 [1.9–2.2]), major depressive disorder (RR=2.0 [1.9–2.1]), and bipolar disorder (RR=1.8 [1.6–2.0]). Ideation-to-attempt transition remained most strongly associated with panic disorder (RR=1.5 [1.3–1.7]), bipolar disorder (RR=1.4 [1.2–1.7]), and sexual abuse (RR=1.4 [1.2–1.7]). Most predictors were significantly but weakly associated with persistence of ideation and plan, while only physical abuse remained associated with repeated suicide attempts (RR=1.3 [1.0–1.8]).
Conclusion. CAs and MDx are strong predictors of both onset of and transition within the STB spectrum, underscoring the importance of implementing early-life prevention interventions.
Idioma: Inglés
DOI: 10.1016/j.psychres.2025.116555
Año: 2025
Publicado en: PSYCHIATRY RESEARCH 350 (2025), 116555 [13 pp.]
ISSN: 0165-1781
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/AC2-00006
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/CB06-02-0046
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/CP21-00078
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI20-00006
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI22-00107
Tipo y forma: Article (Published version)
Área (Departamento): Área Person.Eval.Trat.Psicoló. (Dpto. Psicología y Sociología)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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Method. Poisson regression models within a discrete-time survival framework were constructed using web-based self-report survey data from 72,288 incoming university students across 18 countries (response rate=20.9%; median age=19 years, 57.9% female, 1.4% transgender, 21.0% non-heterosexual). These models examined the associations of four demographic variables, five CAs, and eight MDx with STB outcomes.
Results. Lifetime prevalence of suicidal ideation, plans, and attempts was 47.0%, 26.0%, and 9.6%, respectively; 12-month estimates were 30.6%, 14.0%, and 2.3%. In unadjusted analyses, associations were strongest between lifetime onset of suicidal ideation and CAs (RR range 4.4–7.0), particularly parental psychopathology (relative risk [RR]=7.0 [95% CI 6.5–7.7]), followed by MDx (RR range 1.3–3.0). Of the demographic subgroups, transgender students had highest risk of STB (lifetime ideation onset RR=2.4 [2.3–2.6]; ideation-to-attempt transition RR=1.5 [1.3–1.8]). In fully adjusted models, strongest predictors of lifetime ideation onset were emotional abuse (RR=2.1 [1.9–2.2]), major depressive disorder (RR=2.0 [1.9–2.1]), and bipolar disorder (RR=1.8 [1.6–2.0]). Ideation-to-attempt transition remained most strongly associated with panic disorder (RR=1.5 [1.3–1.7]), bipolar disorder (RR=1.4 [1.2–1.7]), and sexual abuse (RR=1.4 [1.2–1.7]). Most predictors were significantly but weakly associated with persistence of ideation and plan, while only physical abuse remained associated with repeated suicide attempts (RR=1.3 [1.0–1.8]).
Conclusion. CAs and MDx are strong predictors of both onset of and transition within the STB spectrum, underscoring the importance of implementing early-life prevention interventions.
Idioma: Inglés
DOI: 10.1016/j.psychres.2025.116555
Año: 2025
Publicado en: PSYCHIATRY RESEARCH 350 (2025), 116555 [13 pp.]
ISSN: 0165-1781
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/AC2-00006
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/CB06-02-0046
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/CP21-00078
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI20-00006
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI22-00107
Tipo y forma: Article (Published version)
Área (Departamento): Área Person.Eval.Trat.Psicoló. (Dpto. Psicología y Sociología)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. Exportado de SIDERAL (2025-10-17-14:15:03)
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