Resumen: Triple-A (agile, adaptable, and aligned) Supply Chain (SC) has been analyzed as a source of competitive advantage, but the influence of mediating variables in this relationship remains underexplored. This research seeks to advance the Triple-A SC framework by considering and testing the mediating effects of SC collaboration and innovation levels on the Triple-A SC–operational performance (efficiency and responsiveness) relationship. The research model was tested with PLS-SEM using a sample of 277 Spanish manufacturing firms with a minimum of 50 employees from 14 different sectors. The results show that SC collaboration and innovation levels significantly mediate relationships between Triple-A SC and operational performance. Additionally, collaboration level plays a more important role in responsiveness than efficiency, while innovation level has similar effects on both performance dimensions. This work contributes to knowledge on the impact of Triple-A SC on operational performance and alerts managers to the need to strengthen their levels of collaboration with SC partners and innovation over their main competitors. Idioma: Inglés DOI: 10.1080/09537287.2024.2420178 Año: 2024 Publicado en: PRODUCTION PLANNING & CONTROL (2024), [18 pp.] ISSN: 0953-7287 Factor impacto JCR: 5.4 (2024) Categ. JCR: ENGINEERING, INDUSTRIAL rank: 15 / 69 = 0.217 (2024) - Q1 - T1 Categ. JCR: OPERATIONS RESEARCH & MANAGEMENT SCIENCE rank: 15 / 106 = 0.142 (2024) - Q1 - T1 Categ. JCR: ENGINEERING, MANUFACTURING rank: 17 / 71 = 0.239 (2024) - Q1 - T1 Factor impacto SCIMAGO: 2.198 - Computer Science Applications (Q1) - Strategy and Management (Q1) - Management Science and Operations Research (Q1) - Industrial and Manufacturing Engineering (Q1)