Antibodies to Leishmania infantumin peritoneal effusion from a dog with atypical signs of leishmaniosis: treatment and follow-up

Villanueva-Saz, S. (Universidad de Zaragoza) ; Pérez Sala, C. ; Yzuel Estevez, A. ; Fernandez, A. ; Verde, M.T. (Universidad de Zaragoza)

Resumen: A three-year-old entire male French bulldog was brought in with the following clinical signs: apathy, vomiting and abdominal distension. Physical examination showed dehydration, tachypnoea and presence of jaundice. Abdominal radiology revealed the presence of an important loss of details in the abdominal structures compatible with peritoneal effusion, confirmed by abdominal ultrasonography. Findings detected by ultrasonography consisted of splenomegaly with alteration of the echotexture, hepatomegaly with presence of nodules and irregular areas in the liver capsule. An ultrasound-guided sample of the peritoneal fluid was taken for laboratory analysis. Abnormal clinicopathological results included pancytopenia, hyperglobulinaemia, hypoalbuminaemia, and elevation of the hepatic parameters and total bilirubin. High antibodies toLeishmania infantumwere detected by ELISA in serum and peritoneal fluid samples. However, PCR forL infantumshowed a negative result from the peritoneal fluid sample. This is the first reported case of canine leishmaniosis with the specific detection ofL infantumantibodies in peritoneal effusion.

Idioma: Inglés

DOI: 10.1136/vetreccr-2020-001144

Año: 2020

Publicado en: Veterinary Record Case Reports 8, 2 (2020), 001144 [5 pp.]
ISSN: 2052-6121

Factor impacto SCIMAGO: 0.165 - Veterinary (miscellaneous) (Q4)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Farmacología (Dpto. Farmac.Fisiol.y Med.L.F.)
Área (Departamento): Área Medicina y Cirugía Animal (Dpto. Patología Animal)