000163208 001__ 163208
000163208 005__ 20251017161900.0
000163208 0247_ $$2doi$$a10.1016/j.bjpt.2025.101529
000163208 0248_ $$2sideral$$a145663
000163208 037__ $$aART-2025-145663
000163208 041__ $$aeng
000163208 100__ $$aNúñez-Cortés, Rodrigo
000163208 245__ $$aFive-repetition chair-stand test vs. handgrip strength: Which better predicts mortality risk? a follow-up study in 43,605 middle-aged and older adults
000163208 260__ $$c2025
000163208 5203_ $$aBackground: Ageing reduces muscle strength and function, increasing mortality risk. Identifying simple performance markers can guide interventions for healthy ageing.
Objective: To assess the prospective dose-response association of the 5-repetition Chair Stand Test (5-CST) and handgrip strength (HGS) with mortality in middle-aged and older adults. Methods: This prospective study included community-dwelling participants aged 50 years or older from the SHARE study. HGS and 5-CST were assessed at baseline, with all-cause mortality tracked through follow-up interviews. Cox regression with restricted cubic splines was used, controlling for several confounders.
Results: 43,605 participants (mean age (SD): 65.3 (9.1), 54 % women) were included. During a mean follow-up of 7.3 ± 2.2 years, there were 4154 deaths (9.5 %). Both 5-CST and HGS were curvilinearly associated with all- cause mortality. Using the median level of 5-CST as a reference (11 s), 10th percentile of 5-CST (7 s) showed a hazard ratio (HR) of 0.74 (95 %CI: 0.69, 0.80). The 90th percentile (18 s) of 5-CST showed a HR of 1.18 (95 % CI: 1.14, 1.22). Stratified analysis indicated 5-CST was most strongly associated with mortality in women. Regarding HGS, using the median level as a reference (33 kg), the 10th percentile of muscle strength (21 kg) showed a HR of 1.62 (95 %CI: 1.50, 1.75). The 90th percentile (51 kg) of muscle strength showed a HR of 0.58 (95 %CI: 0.52, 0.64).
Conclusion: Both tools provide valuable information, but HGS may be considered more relevant for identifying those at increased mortality risk, while 5-CST may be especially useful in women.
000163208 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000163208 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000163208 700__ $$aAndersen, Lars Louis
000163208 700__ $$aCruz-Montecinos, Carlos
000163208 700__ $$aPolo-López, Ana
000163208 700__ $$0(orcid)0000-0002-7865-3429$$aLópez-Bueno, Rubén
000163208 700__ $$aCalatayud, Joaquín
000163208 773__ $$g29, 6 (2025), 101529 [7 p.]$$pRevista Brasileira de Fisioterapia$$tRevista Brasileira de Fisioterapia$$x1413-3555
000163208 8564_ $$s1595222$$uhttps://zaguan.unizar.es/record/163208/files/texto_completo.pdf$$yVersión publicada$$zinfo:eu-repo/date/embargoEnd/2026-09-23
000163208 8564_ $$s2492600$$uhttps://zaguan.unizar.es/record/163208/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada$$zinfo:eu-repo/date/embargoEnd/2026-09-23
000163208 909CO $$ooai:zaguan.unizar.es:163208$$particulos$$pdriver
000163208 951__ $$a2025-10-17-14:08:06
000163208 980__ $$aARTICLE