Cardiac biomarker release after endurance exercise in male and female adults and adolescents with different pubertal status.

Legaz-Arrese, Alejandro (Universidad de Zaragoza) ; Carranza-García, Luis Enrique ; Navarro-Orocio, Ricardo ; Valadez-Lira, Alberto ; Mayolas-Pi, Carmen (Universidad de Zaragoza) ; Munguía-Izquierdo, Diego ; Reverter-Masía, Joaquín ; George, Keith

Resumen: Objectives. To compare the responses of high-sensitivity cardiac troponin T (hs-cTnT) and NH2-terminal probrain natriuretic peptide (NT-proBNP) after 60 minutes of swimming in male and female adults and adolescents with different pubertal status.
Study design. Adolescent swimmers (25 male and 25 female) and adult swimmers (7 male and 9 female) participated in a 60-minute maximal swimming test with serial assessment of hs-cTnT and NT-proBNP at rest, immediately postexercise, and at 1, 3, 6, 12, and 24 hours postexercise. Adolescents were classified according to pubertal status: Tanner stages 3 (n = 14), 4 (n = 22), and 5 (n = 14).
Results. Exercise resulted in an increase in both biomarkers. hs-cTnT responses to exercise were similar in adolescents with different pubertal status and adults, although there was substantial individual variability in peak hs-cTnT, with the upper reference limit exceeding in 62% of the participants. Postexercise kinetics for hs-cTnT were largely consistent across all groups with a return to near baseline levels 24 hours postexercise. The male participants
showed higher values of hs-cTnT at baseline and postexercise. All groups had similar NT-proBNP responses to acute exercise and recovery. One swimmer exceeded the upper reference limit for NT-proBNP.
Conclusions. An exercise-associated increase in hs-cTnT and NT-proBNP occurred in response to a 60-minute maximal swimming test that was independent of pubertal status/adolescent vs adults. The present data also suggests that baseline and postexercise hs-cTnT values are higher in male compared with female, with no sex differences in NT-proBNP values.

Idioma: Inglés

DOI: 10.1016/j.jpeds.2017.08.061

Año: 2017

Publicado en: Journal of Pediatrics 191 (2017), 96-102
ISSN: 0022-3476

Factor impacto JCR: 3.667 (2017)

Categ. JCR: PEDIATRICS rank: 8 / 124 = 0.065 (2017) - Q1 - T1

Factor impacto SCIMAGO: 1.522 - Pediatrics, Perinatology and Child Health (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-16767

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Educación Física y Depor. (Dpto. Fisiatría y Enfermería)