Inflammation and coronary artery disease: The exercise paradox

Sanchis-Gomar, F. ; Mayolas-Pi, C. (Universidad de Zaragoza) ; Garatachea, N. (Universidad de Zaragoza)

Resumen: To the Editor,
While physical inactivity has been identified in epidemiological studies as an important risk factor of coronary artery disease (CAD), regular physical activity (PA) seems to be effective in the prevention and/or treatment of CAD by modulating classic risk factors. Although the mechanisms by which exercise benefits CAD patients has been identified [1], scientific evidence, and hence consensus, evaluating the positive and/or negative effects of inflammatory response to exercise in CAD is still lacking. Cwikiel et al. [2] evaluated the inflammatory effects of exercise in subjects with and without CAD. They reported that patients with symptoms suggestive of CAD showed an altered inflammatory response, but not more pronounced than subjects without CAD, after acute strenuous exercise. In this regard, Sponder et al. [3] also studied the effects of long-term physical activity (PA) on the circulating soluble receptor of advanced glycation end products (sRAGE) levels, finally showing that its levels significantly increased after long-term PA...

Idioma: Inglés

DOI: 10.1016/j.cyto.2018.09.020

Año: 2018

Publicado en: CYTOKINE 111 (2018), 371-372
ISSN: 1043-4666

Factor impacto JCR: 3.078 (2018)

Categ. JCR: BIOCHEMISTRY & MOLECULAR BIOLOGY rank: 131 / 294 = 0.446 (2018) - Q2 - T2
Categ. JCR: IMMUNOLOGY rank: 84 / 157 = 0.535 (2018) - Q3 - T2
Categ. JCR: CELL BIOLOGY rank: 110 / 191 = 0.576 (2018) - Q3 - T2

Factor impacto SCIMAGO: 1.322 - Biochemistry (Q1) - Hematology (Q1) - Molecular Biology (Q1) - Immunology and Allergy (Q1) - Immunology (Q1)

Tipo y forma: (PostPrint)

Área (Departamento): Área Educación Física y Depor. (Dpto. Fisiatría y Enfermería)