000168450 001__ 168450
000168450 005__ 20260205155159.0
000168450 0247_ $$2doi$$a10.3389/fphar.2025.1721689
000168450 0248_ $$2sideral$$a147894
000168450 037__ $$aART-2025-147894
000168450 041__ $$aeng
000168450 100__ $$aLlor, Carl
000168450 245__ $$aAntibiotic use for respiratory tract infections in nursing homes: a multicentre cross-sectional study
000168450 260__ $$c2025
000168450 5060_ $$aAccess copy available to the general public$$fUnrestricted
000168450 5203_ $$aIntroduction: To evaluate the use of antibiotic treatment for respiratory tract infections (RTIs) in nursing homes in Spain, assess whether they were indicated based on current guidelines, and identify predictors of both use and inappropriate use of antibiotics.
Methods: Cross-sectional study carried out in 34 nursing homes in five areas in Spain. Nursing staff self-registered residents related to antibiotic use for RTIs in February-April 2023. Nursing staff recorded data on residents with RTIs, including demographics, symptoms, diagnoses, and antibiotic use. Logistic regression models were applied to identify predictors of antibiotic prescription and inappropriate use based on clinical guidelines.
Results: Among 533 recorded RTI cases, the most common diagnoses were common cold (19.7%) and acute bronchitis (18.8%). Antibiotics were prescribed in 77.5% of cases, mainly for otitis media, tonsillitis, and pneumonia, with amoxicillin-clavulanate being the most frequent (34%). Of 328 prescriptions assessed, 63.1% were deemed unnecessary. Factors strongly associated with antibiotic use included confusion (odds ratio 4.72; p = 0.005), perceived demand for antibiotics (OR 3.83; p < 0.001), and fever (OR 3.27; p = 0.005), whereas rhinorrhea reduced the likelihood of prescription (OR 0.23; p < 0.001).
Discussion: The findings reveal substantial overuse of antibiotics for RTIs in nursing homes and highlight the need for targeted interventions to promote guideline-based prescribing and reduce inappropriate use.
000168450 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000168450 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000168450 700__ $$aMorros, Rosa
000168450 700__ $$aMateos-Nozal, Jesús
000168450 700__ $$aZárate Sáez, Carlota Manuela
000168450 700__ $$aVaquero Pinto, María N.
000168450 700__ $$aRodríguez Jiménez, Consuelo
000168450 700__ $$aSáez Bejar, Carmen
000168450 700__ $$0(orcid)0000-0002-5494-6550$$aMagallón-Botaya, Rosa$$uUniversidad de Zaragoza
000168450 700__ $$aMatovelle, Priscila
000168450 700__ $$aNavarro Sanmartín, Alicia
000168450 700__ $$aLópez Pérez, Elena
000168450 700__ $$aGarcía-Sangenís, Ana
000168450 700__ $$aMonfà, Ramon
000168450 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000168450 773__ $$g16 (2025), [11 pp.]$$pFront. pharmacol.$$tFrontiers in Pharmacology$$x1663-9812
000168450 8564_ $$s2401349$$uhttps://zaguan.unizar.es/record/168450/files/texto_completo.pdf$$yVersión publicada
000168450 8564_ $$s2206034$$uhttps://zaguan.unizar.es/record/168450/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000168450 909CO $$ooai:zaguan.unizar.es:168450$$particulos$$pdriver
000168450 951__ $$a2026-02-05-14:36:50
000168450 980__ $$aARTICLE