000170280 001__ 170280
000170280 005__ 20260410165451.0
000170280 0247_ $$2doi$$a10.1021/acssuschemeng.6c00237
000170280 0248_ $$2sideral$$a148849
000170280 037__ $$aART-2026-148849
000170280 041__ $$aeng
000170280 100__ $$aClemente, Alberto$$uUniversidad de Zaragoza
000170280 245__ $$aBiobased Functional Ionic Liquids for a Novel Approach to Sonogashira Coupling in the Absence of Copper and External Bases
000170280 260__ $$c2026
000170280 5060_ $$aAccess copy available to the general public$$fUnrestricted
000170280 5203_ $$aWe report the first use of functional renewable ionic liquids, with favorable ecotoxicological profiles toward representative microorganisms, in efficient and recoverable nanoparticle-based catalytic systems to promote copper-free Sonogashira coupling reactions in the absence of externally added bases. These systems, based on palladium nanoparticles immobilized on glycerol-derived [N201]X ionic liquids bearing basic anions, achieved the coupling of differently substituted substrates in 1 h. Contrarily, analogous ionic liquids without basic character and classic imidazolium ionic liquids ─[BMIm]PF6─ were not active for the test reaction at all, even if a large excess of an external base was added. Different product selectivities were observed, as a function of the different hydrophilic nature (and water content) of the ionic liquid. Therefore, this novel approach improves the catalytic results under milder conditions and minimizes waste generation, as observed in the green metrics determined for the benchmark process, offering a more sustainable and effective alternative in cross-coupling transformations.
000170280 536__ $$9info:eu-repo/grantAgreement/ES/AEI/AEI PID2021-125762NB-I00$$9info:eu-repo/grantAgreement/ES/DGA/E37-23R
000170280 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000170280 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000170280 700__ $$aCambronero-Arregui, Jorge
000170280 700__ $$0(orcid)0000-0003-2076-844X$$aAínsa, José A.$$uUniversidad de Zaragoza
000170280 700__ $$0(orcid)0000-0002-2676-8814$$aPires, Elísabet$$uUniversidad de Zaragoza
000170280 700__ $$0(orcid)0000-0003-1570-4257$$aMayoral, José A.$$uUniversidad de Zaragoza
000170280 700__ $$0(orcid)0000-0002-3256-2089$$aLeal-Duaso, Alejandro
000170280 7102_ $$11011$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Microbiología
000170280 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000170280 773__ $$g(2026), [7 pp.]$$pACS sustain. chem. & eng.$$tACS Sustainable Chemistry and Engineering$$x2168-0485
000170280 8564_ $$s1961913$$uhttps://zaguan.unizar.es/record/170280/files/texto_completo.pdf$$yVersión publicada
000170280 8564_ $$s3149065$$uhttps://zaguan.unizar.es/record/170280/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000170280 909CO $$ooai:zaguan.unizar.es:170280$$particulos$$pdriver
000170280 951__ $$a2026-04-10-13:45:45
000170280 980__ $$aARTICLE