Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs
Garrido, V. ; Sánchez, S. ; San Román, B. ; Zabalza-Baranguá, A. ; Díaz-Tendero, Y. ; de Frutos, C. ; Mainar-Jaime, R. (Universidad de Zaragoza) ; Grilló, M.J
Resumen: Background
Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This procedure is considered the most reliable for diagnosing salmonellosis in apparently healthy pigs. The presence of simultaneous infections by different Salmonella strains in the same animal has never been reported and could have important epidemiological implications.
Results
Fourteen finishing pigs belonging to 14 farms that showed high salmonellosis prevalence and a variety of circulating Salmonella strains, were found infected by Salmonella spp, and 7 of them were simultaneously infected with strains of 2 or 3 different serotypes. Typhimurium isolates showing resistance to several antimicrobials and carrying mobile integrons were the most frequently identified in the colonized MLN. Four animals were found infected by Salmonella spp. of a single serotype (Rissen or Derby) but showing 2 or 3 different antimicrobial resistance profiles, without evidence of mobile genetic element exchange in vivo.
Conclusion
This is the first report clearly demonstrating that pigs naturally infected by Salmonella may harbour different Salmonella strains simultaneously. This may have implications in the interpretation of results from baseline studies, and also help to better understand human salmonellosis outbreaks and the horizontal transmission of antimicrobial resistance genes.
Idioma: Inglés
DOI: 10.1186/1746-6148-10-59
Año: 2014
Publicado en: BMC VETERINARY RESEARCH 10, 59 (2014), [6 pp.]
ISSN: 1746-6148
Factor impacto JCR: 1.777 (2014)
Categ. JCR: VETERINARY SCIENCES rank: 21 / 132 = 0.159 (2014) - Q1 - T1
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Sanidad Animal (Departamento de Patología Animal)
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Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This procedure is considered the most reliable for diagnosing salmonellosis in apparently healthy pigs. The presence of simultaneous infections by different Salmonella strains in the same animal has never been reported and could have important epidemiological implications.
Results
Fourteen finishing pigs belonging to 14 farms that showed high salmonellosis prevalence and a variety of circulating Salmonella strains, were found infected by Salmonella spp, and 7 of them were simultaneously infected with strains of 2 or 3 different serotypes. Typhimurium isolates showing resistance to several antimicrobials and carrying mobile integrons were the most frequently identified in the colonized MLN. Four animals were found infected by Salmonella spp. of a single serotype (Rissen or Derby) but showing 2 or 3 different antimicrobial resistance profiles, without evidence of mobile genetic element exchange in vivo.
Conclusion
This is the first report clearly demonstrating that pigs naturally infected by Salmonella may harbour different Salmonella strains simultaneously. This may have implications in the interpretation of results from baseline studies, and also help to better understand human salmonellosis outbreaks and the horizontal transmission of antimicrobial resistance genes.
Idioma: Inglés
DOI: 10.1186/1746-6148-10-59
Año: 2014
Publicado en: BMC VETERINARY RESEARCH 10, 59 (2014), [6 pp.]
ISSN: 1746-6148
Factor impacto JCR: 1.777 (2014)
Categ. JCR: VETERINARY SCIENCES rank: 21 / 132 = 0.159 (2014) - Q1 - T1
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Sanidad Animal (Departamento de Patología Animal)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. Exportado de SIDERAL (2017-05-04-09:41:21)
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Artículos > Artículos por área > Sanidad Animal
Registro creado el 2015-11-26, última modificación el 2017-05-04