000032488 001__ 32488
000032488 005__ 20170504094304.0
000032488 0247_ $$2doi$$a10.1186/1746-6148-10-59
000032488 0248_ $$2sideral$$a86668
000032488 037__ $$aART-2014-86668
000032488 041__ $$aeng
000032488 100__ $$aGarrido, V.
000032488 245__ $$aSimultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs
000032488 260__ $$c2014
000032488 5060_ $$aAccess copy available to the general public$$fUnrestricted
000032488 5203_ $$aBackground
Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis prevalence in fattening pigs in Europe are based on direct pathogen isolation from mesenteric lymph nodes (MLN). This procedure is considered the most reliable for diagnosing salmonellosis in apparently healthy pigs. The presence of simultaneous infections by different Salmonella strains in the same animal has never been reported and could have important epidemiological implications.
Results
Fourteen finishing pigs belonging to 14 farms that showed high salmonellosis prevalence and a variety of circulating Salmonella strains, were found infected by Salmonella spp, and 7 of them were simultaneously infected with strains of 2 or 3 different serotypes. Typhimurium isolates showing resistance to several antimicrobials and carrying mobile integrons were the most frequently identified in the colonized MLN. Four animals were found infected by Salmonella spp. of a single serotype (Rissen or Derby) but showing 2 or 3 different antimicrobial resistance profiles, without evidence of mobile genetic element exchange in vivo.
Conclusion
This is the first report clearly demonstrating that pigs naturally infected by Salmonella may harbour different Salmonella strains simultaneously. This may have implications in the interpretation of results from baseline studies, and also help to better understand human salmonellosis outbreaks and the horizontal transmission of antimicrobial resistance genes.
000032488 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000032488 590__ $$a1.777$$b2014
000032488 591__ $$aVETERINARY SCIENCES$$b21 / 132 = 0.159$$c2014$$dQ1$$eT1
000032488 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000032488 700__ $$aSánchez, S.
000032488 700__ $$aSan Román, B.
000032488 700__ $$aZabalza-Baranguá, A.
000032488 700__ $$aDíaz-Tendero, Y.
000032488 700__ $$ade Frutos, C.
000032488 700__ $$0(orcid)0000-0001-5442-7702$$aMainar-Jaime, R.$$uUniversidad de Zaragoza
000032488 700__ $$aGrilló, M.J
000032488 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDepartamento de Patología Animal$$cSanidad Animal
000032488 773__ $$g10, 59 (2014), [6 pp.]$$pBMC Vet. Res.$$tBMC VETERINARY RESEARCH$$x1746-6148
000032488 8564_ $$s198468$$uhttps://zaguan.unizar.es/record/32488/files/texto_completo.pdf$$yVersión publicada
000032488 8564_ $$s110818$$uhttps://zaguan.unizar.es/record/32488/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000032488 909CO $$ooai:zaguan.unizar.es:32488$$particulos$$pdriver
000032488 951__ $$a2017-05-04-09:41:21
000032488 980__ $$aARTICLE