Kinetic theory modeling and efficient numerical simulation of gene regulatory networks based on qualitative descriptions
Resumen: n this work, we begin by considering the qualitative modeling of biological regulatory systems using process hitting, from which we define its probabilistic counterpart by considering the chemical master equation within a kinetic theory framework. The last equation is efficiently solved by considering a separated representation within the proper generalized decomposition framework that allows circumventing the so-called curse of dimensionality. Finally, model parameters can be added as extra-coordinates in order to obtain a parametric solution of the model
Idioma: Inglés
DOI: 10.3390/e17041896
Año: 2015
Publicado en: ENTROPY 17, 4 (2015), 1896-1915
ISSN: 1099-4300

Factor impacto JCR: 1.743 (2015)
Categ. JCR: PHYSICS, MULTIDISCIPLINARY rank: 25 / 78 = 0.321 (2015) - Q2 - T1
Factor impacto SCIMAGO:

Tipo y forma: Article (Published version)
Área (Departamento): Mec. de Medios Contínuos y Teor. de Estructuras (Departamento de Ingeniería Mecánica)

Creative Commons You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.


Exportado de SIDERAL (2017-05-04-09:05:27)

Este artículo se encuentra en las siguientes colecciones:
Articles > Artículos por área > Mec. de Medios Contínuos y Teor. de Estructuras



 Record created 2016-01-21, last modified 2017-05-04


Versión publicada:
 PDF
Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)