Vitamin D deficiency in Europe: Pandemic?

Cashman, K.D. ; Dowling, K.G. ; Škrabáková, Z. ; Gonzalez-Gross, M. ; Valtueña, J . ; De Henauw, S. ; Moreno, L. (Universidad de Zaragoza) ; Damsgaard, C.T. ; Michaelsen, K.F. ; Mølgaard, C. ; Jorde, R. ; Grimnes, G. ; Moschonis, G. ; Mavrogianni, C. ; Manios, Y. ; Thamm, M. ; Mensink, G.B.M. ; Rabenberg, M. ; Busch, M.A. ; Cox, L. ; Meadows, S. ; Goldberg, G. ; Prentice, A. ; Dekker, J.M. ; Nijpels, G. ; Pilz, S. ; Swart, K.M. ; Van Schoor, N.M. ; Lips, P. ; Eiriksdottir, G. ; Gudnason, V. ; Cotch, M.F. ; Koskinen, S. ; Lamberg-Allardt, C. ; Durazo-Arvizu, R. ; Sempos, C.T. ; Kiely, M.

Resumen: Background: Vitamin D deficiency has been described as being pandemic, but serum 25-hydroxyVitamin D 25(OH)D] distribution data for the European Union are of very variable quality. The NIHled international Vitamin D Standardization Program (VDSP) has developed protocols for standardizing existing 25(OH)D values from national health/nutrition surveys. Objective: This study applied VDSP protocols to serum 25(OH)D data from representative childhood/teenage and adult/older adult European populations, representing a sizable geographical footprint, to better quantify the prevalence of Vitamin D deficiency in Europe. Design: The VDSP protocols were applied in 14 population studies reanalysis of subsets of serum 25(OH)D in 11 studies and complete analysis of all samples from 3 studies that had not previously measured it] by using certified liquid chromatography-tandem mass spectrometry on biobanked sera. These data were combined with standardized serum 25(OH)D data from 4 previously standardized studies (for a total n = 55,844). Prevalence estimates of Vitamin D deficiency using various serum 25(OH)D thresholds] were generated on the basis of standardized 25(OH)D data. Results: An overall pooled estimate, irrespective of age group, ethnic mix, and latitude of study populations, showed that 13.0% of the 55,844 European individuals had serum 25(OH)D concentrations <30 nmol/L on average in the year, with 17.7% and 8.3% in those sampled during the extended winter (October-March) and summer (April-November) periods, respectively. According to an alternate suggested definition of Vitamin D deficiency (<50 nmol/ L), the prevalence was 40.4%. Dark-skinned ethnic subgroups had much higher (3- to 71-fold) prevalence of serum 25(OH)D <30 nmol/L than did white populations. Conclusions: Vitamin D deficiency is evident throughout the European population at prevalence rates that are concerning and that require action from a public health perspective. What direction these strategies take will depend on European policy but should aim to ensure Vitamin D intakes that are protective against Vitamin D deficiency in the majority of the European population.

Idioma: Inglés

DOI: 10.3945/ajcn.115.120873

Año: 2016

Publicado en: American Journal of Clinical Nutrition 103, 4 (2016), 1033-1044
ISSN: 0002-9165

Factor impacto JCR: 6.926 (2016)

Categ. JCR: NUTRITION & DIETETICS rank: 3 / 81 = 0.037 (2016) - Q1 - T1

Factor impacto SCIMAGO: 3.782 - Nutrition and Dietetics (Q1) - Medicine (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/EC/FP7/613977/EU/Food-based solutions for Optimal vitamin D Nutrition and health through the life cycle/ODIN

Tipo y forma: Article (Published version)

Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)