000048684 001__ 48684
000048684 005__ 20200221144248.0
000048684 0247_ $$2doi$$a10.1038/srep23622
000048684 0248_ $$2sideral$$a94673
000048684 037__ $$aART-2016-94673
000048684 041__ $$aeng
000048684 100__ $$0(orcid)0000-0002-1184-5901$$aLozano, A.
000048684 245__ $$aControl strategies of 3-cell Central Pattern Generator via global stimuli
000048684 260__ $$c2016
000048684 5060_ $$aAccess copy available to the general public$$fUnrestricted
000048684 5203_ $$aThe study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in the emergence of pathological rhythmic brain activity in different diseases, like Parkinson''s disease. We show how, with a suitable combination of short and weak global inhibitory and excitatory stimuli over the whole network, we can switch between different stable bursting patterns in small neuron networks (in our case a 3-neuron network). We develop a systematic study showing and explaining the effects of applying the pulses at different moments. Moreover, we compare the technique on a completely symmetric network and on a slightly perturbed one (a much more realistic situation). The present approach of using global stimuli may allow to avoid undesirable synchronization patterns with nonaggressive stimuli.
000048684 536__ $$9info:eu-repo/grantAgreement/ES/UZ/CUD2015-CIE-05$$9info:eu-repo/grantAgreement/ES/MICINN/MTM2015-64095-P$$9info:eu-repo/grantAgreement/ES/MICINN/MTM2013-46337-C2-2-P$$9info:eu-repo/grantAgreement/ES/MICINN/MTM2012-31883$$9info:eu-repo/grantAgreement/ES/DGA/E48$$9info:eu-repo/grantAgreement/ES/DGA/E15
000048684 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000048684 590__ $$a4.259$$b2016
000048684 591__ $$aMULTIDISCIPLINARY SCIENCES$$b10 / 63 = 0.159$$c2016$$dQ1$$eT1
000048684 592__ $$a1.691$$b2016
000048684 593__ $$aMultidisciplinary$$c2016$$dQ1
000048684 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000048684 700__ $$0(orcid)0000-0003-3426-105X$$aRodriguez, M.
000048684 700__ $$0(orcid)0000-0002-8089-343X$$aBarrio, R.$$uUniversidad de Zaragoza
000048684 7102_ $$12005$$2595$$aUniversidad de Zaragoza$$bDpto. Matemática Aplicada$$cÁrea Matemática Aplicada
000048684 773__ $$g6 (2016), 23622 [10 pp]$$pSci. rep.$$tSCIENTIFIC REPORTS$$x2045-2322
000048684 8564_ $$s3798618$$uhttps://zaguan.unizar.es/record/48684/files/texto_completo.pdf$$yVersión publicada
000048684 8564_ $$s114550$$uhttps://zaguan.unizar.es/record/48684/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000048684 909CO $$ooai:zaguan.unizar.es:48684$$particulos$$pdriver
000048684 951__ $$a2020-02-21-13:26:32
000048684 980__ $$aARTICLE