Resumen: Background: We studied herein the predictive value for panic severity of three well-based vulnerability factors: personality traits (neuroticism and extraversion; NEO-PI-R), anxiety sensitivity (ASI), and perceived control (ACQ-R). Method: The sample was composed of 52 participants diagnosed with panic disorder, with or without agoraphobia, according to DSM-IV-TR criteria. Results: Our results revealed that the anxiety facet is a better predictor of panic severity than neuroticism. Anxiety sensitivity increases the predictive value for panic severity and, finally, perception of control of emotions is the only perception control subscale that increases the predictive value for panic severity more than the anxiety facet and anxiety sensitivity. Conclusions: This finding supports the assumption of the importance of taking into account the assessment of the lower order dimensions of the vulnerability factors in the field of psychopathology studies. Furthermore, the predictive value of perception of control of emotions indicates the importance of this specific vulnerability factor in the etiology of panic disorder (with or without agoraphobia) and, thus, shows the necessity to include emotion regulation strategies in the psychological treatments. Idioma: Inglés DOI: 10.7334/psicothema2015.223 Año: 2016 Publicado en: Psicothema 28, 2 (2016), 167-173 ISSN: 0214-9915 Factor impacto JCR: 1.344 (2016) Categ. JCR: PSYCHOLOGY, MULTIDISCIPLINARY rank: 61 / 128 = 0.477 (2016) - Q2 - T2 Factor impacto SCIMAGO: 0.676 - Psychology (miscellaneous) (Q2)