A parametric model for analysing atherosclerotic arteries: On the FSI coupling

Cilla, M. ; Borrás, I. ; Peña, E. (Universidad de Zaragoza) ; Martínez, M.A. (Universidad de Zaragoza) ; Malvè, M.

Resumen: There are many evidences that coronary plaque is not only dependent on the formation and progression of atherosclerosis, but also on the vascular remodelling response. If the local wall shear stress is low, a proliferative plaque may develop. Local inflammatory response will stimulate the formation of a plaque prone to rupture with superimposed thrombus formation (vulnerable plaque). Furthermore, the role of the wall shear stress in the genesis and the development of atherosclerotic diseases has been recently intensively investigated, examining its relationship with the presence of lesions and the intima media thickness. Due to the important role of pulsating blood flow, pressure and hemodynamics factors in atheroma growth, a Fluid Structure Interaction (FSI) parametric study of a 3D atherosclerotic artery has been carried out, with aim of studying the main geometrical risk factors in terms of plaque vulnerability.

Idioma: Inglés

DOI: 10.1016/j.icheatmasstransfer.2015.06.017

Año: 2015

Publicado en: INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER 67 (2015), 29-38
ISSN: 0735-1933

Factor impacto JCR: 2.559 (2015)

Categ. JCR: THERMODYNAMICS rank: 9 / 58 = 0.155 (2015) - Q1 - T1
Categ. JCR: MECHANICS rank: 16 / 135 = 0.119 (2015) - Q1 - T1

Factor impacto SCIMAGO: 1.618 - Atomic and Molecular Physics, and Optics (Q1) - Condensed Matter Physics (Q1) - Chemical Engineering (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/B137-09
Financiación: info:eu-repo/grantAgreement/ES/MINECO/DPI2013-44391-P

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)