Involvement of the serotonin pathway in ileal neruomotor dysfunction associated with TLR2 and TLR4 inhibition in juvenille mice

Marsilio, I. ; Caputi, V. ; Cerantola, S. ; Latorre Duque, E. ; Paquola, A. ; Pattarello, A. ; Orso, G. ; Mesonero, J.E. (Universidad de Zaragoza) ; Bertazzo, A. ; Giron, M.C.

Resumen: Objective: Oxidized phospholipids (OxPAPC) inhibit TLR2-and TLR4-dependent signalling recognized to be involved in ensuring enteric nervous system (ENS) integrity. This study aimed to evaluate the effects of in vivo OxPAPC administration on ileal contractility and serotonin pathway in juvenile mice.

Idioma: Inglés

DOI: 10.1111/nmo.13180

Año: 2017

Publicado en: NEUROGASTROENTEROLOGY AND MOTILITY 29, Suppl. 2 (2017), 14 [1 p.]
ISSN: 1350-1925

Factor impacto JCR: 3.842 (2017)

Categ. JCR: CLINICAL NEUROLOGY rank: 45 / 197 = 0.228 (2017) - Q1 - T1
Categ. JCR: NEUROSCIENCES rank: 80 / 261 = 0.307 (2017) - Q2 - T1
Categ. JCR: GASTROENTEROLOGY & HEPATOLOGY rank: 23 / 80 = 0.287 (2017) - Q2 - T1

Factor impacto SCIMAGO: 2.095 - Endocrine and Autonomic Systems (Q1) - Physiology (Q1) - Gastroenterology (Q1)

Tipo y forma: Comunicación congreso (Versión definitiva)

Área (Departamento): Área Fisiología (Dpto. Farmacología y Fisiolog.)