Michaelis-Menten dynamics of a polymer chain out of a dichotomous ATP-based motor
Fiasconaro, Alessandro (Universidad de Zaragoza) ; Mazo, Juan José (Universidad de Zaragoza) ; Falo, Fernando (Universidad de Zaragoza)
Resumen: We present a model of an ATP-fueled molecular machine which pushes a polymer through a pore channel. The machine acts between two levels (working–waiting), and the working one remains active for a fixed time giving a constant force. The activation rate of the machine can be put in relationship with the available ATP concentration in the solution, which gives the necessary energy supply. The translocation time shows a monotonic behaviour as a function of the activation frequency, and the velocity follows a Michaelis–Menten (MM) law that arises naturally in this description. The estimation of the stall force of the motor follows a corrected MM law which yet is to be checked in experimental investigations. The results presented here agree with recent biological experimental findings.
Idioma: Inglés
DOI: 10.1088/1367-2630/14/2/023004
Año: 2012
Publicado en: NEW JOURNAL OF PHYSICS 14 (2012), 023004 [13 pp.]
ISSN: 1367-2630
Factor impacto JCR: 4.063 (2012)
Categ. JCR: PHYSICS, MULTIDISCIPLINARY rank: 9 / 83 = 0.108 (2012) - Q1 - T1
Financiación: info:eu-repo/grantAgreement/ES/MINECO/FIS2008-01240
Financiación: info:eu-repo/grantAgreement/ES/MINECO/FIS2011-25167
Tipo y forma: Article (Published version)
Área (Departamento): Física de la Materia Condensada (Departamento de Física de la Materia Condensada)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
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Idioma: Inglés
DOI: 10.1088/1367-2630/14/2/023004
Año: 2012
Publicado en: NEW JOURNAL OF PHYSICS 14 (2012), 023004 [13 pp.]
ISSN: 1367-2630
Factor impacto JCR: 4.063 (2012)
Categ. JCR: PHYSICS, MULTIDISCIPLINARY rank: 9 / 83 = 0.108 (2012) - Q1 - T1
Financiación: info:eu-repo/grantAgreement/ES/MINECO/FIS2008-01240
Financiación: info:eu-repo/grantAgreement/ES/MINECO/FIS2011-25167
Tipo y forma: Article (Published version)
Área (Departamento): Física de la Materia Condensada (Departamento de Física de la Materia Condensada)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. Exportado de SIDERAL (2017-10-30-13:31:08)
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Record created 2017-10-30, last modified 2017-10-31