An expedient synthesis of resveratrol through a highly recoverable palladium catalyst
Martínez, Alejandro V. ; García, José I. ; Mayoral, José A. (Universidad de Zaragoza)
Resumen: A straightforward two-step synthesis of resveratrol is described, with total isolated yields in the range of 75–80%. The key synthetic step, a Heck–Mizoroki C[sbnd]C cross-coupling reaction, is efficiently promoted by a heterogeneous catalyst consisting of palladium nanoparticles supported on synthetic clay. This solid catalyst is quite handy and displays high stability and robustness under reaction conditions. The catalyst can be easily recovered and reused at least 10 times, which improves the overall catalytic efficiency of the system. Moreover, the use of solvents is limited, and the reaction procedure allows a facile separation and purification of the desired product, free from the concomitant ionic by-product and from palladium contamination.
Idioma: Inglés
DOI: 10.1016/j.tet.2016.08.074
Año: 2017
Publicado en: TETRAHEDRON 73, 38 (2017), 5581-5584
ISSN: 0040-4020
Factor impacto JCR: 2.377 (2017)
Categ. JCR: CHEMISTRY, ORGANIC rank: 23 / 57 = 0.404 (2017) - Q2 - T2
Factor impacto SCIMAGO: 0.8 - Biochemistry (Q2) - Organic Chemistry (Q2) - Drug Discovery (Q2)
Financiación: info:eu-repo/grantAgreement/ES/DGA/E11
Financiación: info:eu-repo/grantAgreement/ES/MINECO/CTQ2014-52367-R
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
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Idioma: Inglés
DOI: 10.1016/j.tet.2016.08.074
Año: 2017
Publicado en: TETRAHEDRON 73, 38 (2017), 5581-5584
ISSN: 0040-4020
Factor impacto JCR: 2.377 (2017)
Categ. JCR: CHEMISTRY, ORGANIC rank: 23 / 57 = 0.404 (2017) - Q2 - T2
Factor impacto SCIMAGO: 0.8 - Biochemistry (Q2) - Organic Chemistry (Q2) - Drug Discovery (Q2)
Financiación: info:eu-repo/grantAgreement/ES/DGA/E11
Financiación: info:eu-repo/grantAgreement/ES/MINECO/CTQ2014-52367-R
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2019-07-09-11:51:00)
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Record created 2017-12-13, last modified 2019-07-09