Innovations in Glaucoma Surgery: Improving the Results

Figus, M. ; Melamed, S. ; Ferreras, A. (Universidad de Zaragoza) ; Marchini, G. ; Costa, V.P.

Resumen: Glaucoma still represents the most frequent cause of irreversible blindness worldwide. The technological advances lead to innovative surgeries, which are rapidly introduced in clinical practice. New devices to lower intraocular pressure without opening the eye wall, bypassing the trabecular meshwork, or shunting the aqueous humor to the suprachoroidal space have been approved undergoing clinical assessment within clinical trials. Currently, other devices under evaluation are showing promising results. Although these methods will increase the options available for glaucoma surgeons, it is unclear if they could replace the present standard surgeries, such as trabeculectomy, deep sclerectomy, and glaucoma drainage devices. Moreover, the standard procedures are continuously modified in different ways to become safer and more effective.
In this issue L. Choritz et al. investigate whether increased concentrations of endothelin-1 in the aqueous humor samples of glaucoma patients influenced wound healing and bleb fibrosis after standard trabeculectomy with mitomycin C. Endothelin-1 is a potent vasoconstrictor produced in the eye by the ciliary epithelium and to be released into the aqueous humor. It has been implicated in the pathophysiology of glaucoma. Endothelin-1 is believed to be involved in the regulation of intraocular pressure (IOP) via effects on the contractility of ciliary muscle and trabecular meshwork...

Idioma: Inglés

DOI: 10.1155/2016/5856075

Año: 2016

Publicado en: Journal of Ophthalmology 2016, 5856075 (2016), [2 pp]
ISSN: 2090-004X

Factor impacto JCR: 1.712 (2016)

Categ. JCR: OPHTHALMOLOGY rank: 35 / 59 = 0.593 (2016) - Q3 - T2
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 84 / 128 = 0.656 (2016) - Q3 - T2

Factor impacto SCIMAGO: 0.812 - Ophthalmology (Q2)

Tipo y forma: (Published version)

Área (Departamento): Área Oftalmología (Dpto. Cirugía,Ginecol.Obstetr.)