000070727 001__ 70727
000070727 005__ 20180613084938.0
000070727 037__ $$aCOMPON-2018-0002
000070727 041__ $$aeng
000070727 100__ $$00000-0003-4130-5866$$aRamírez, J.
000070727 245__ $$aQuantification of T-wave Morphological Variability Using Time-warping Methods
000070727 260__ $$c2017
000070727 506__ $$aAccess copy available to the general public$$fUnrestricted
000070727 5203_ $$aThe aim of this study is to quantify the variation of the T-wave morphology during a 24-hour electrocardiogram (ECG) recording. Two ECG-derived markers are presented to quantify T-wave morphological variability in the temporal, dw, and amplitude, da, domains. Two additional markers, dNLw and dNLa, that only capture the non-linear component of dw and da are also proposed. The proposed markers are used to quantify T-wave time and amplitude variations in 500 24-hour ECG recordings from chronic heart failure patients. Additionally, two mean warped T-waves, used in the calculation of those markers, are proposed to compensate for the rate dependence of the T-wave morphology. Statistical analysis is used to evaluate the correlation between dw, dNLw, da and dNLa and the maximum intra-subject RR range, ΔRR. Results show that the mean warped T-wave is able to compensate for the morphological differences due to RR dynamics. Moreover, the metrics dw and dNLw are correlated with ΔRR, but da and dNLa are not. The proposed dw and dNLw quantify variations in the temporal domain of the T-wave that are correlated with the RR range and, thus, could possibly reflect the variations of dispersion of repolarization due to changes in heart rate.
000070727 536__ $$9info:eu-repo/grant/Agreement/ES/MINECO TIN2013-41998- R
000070727 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000070727 6531_ $$aElectrocardiogram
000070727 655_4 $$aComunicación
000070727 6531_ $$amorphological variability
000070727 6531_ $$arepolarization
000070727 6531_ $$aT-wave time-warping
000070727 700__ $$aOrini, M.
000070727 700__ $$00000-0002-1960-407X$$aPueyo, E.
000070727 700__ $$00000-0003-3434-9254$$aLaguna, P.
000070727 773__ $$dSingapore$$gEuropean Medical and Biological Engineering Confernce (2017)
000070727 8564_ $$s440361$$uhttps://zaguan.unizar.es/record/70727/files/COMPON-2018-0002.pdf
000070727 909CO $$ooai:zaguan.unizar.es:70727$$pcomunicaciones-ponencias
000070727 980__ $$aCOMPON