000074805 001__ 74805 000074805 005__ 20200117221604.0 000074805 0247_ $$2doi$$a10.1371/journal.pone.0200197 000074805 0248_ $$2sideral$$a107101 000074805 037__ $$aART-2018-107101 000074805 041__ $$aeng 000074805 100__ $$0(orcid)0000-0002-3979-4528$$aRemón, L.$$uUniversidad de Zaragoza 000074805 245__ $$aFractal-structured multifocal intraocular lens 000074805 260__ $$c2018 000074805 5060_ $$aAccess copy available to the general public$$fUnrestricted 000074805 5203_ $$aIn this work, we present a new concept of IOL design inspired by the demonstrated properties of reduced chromatic aberration and extended depth of focus of Fractal zone plates. A detailed description of a proof of concept IOL is provided. The result was numerically characterized, and fabricated by lathe turning. The prototype was tested in vitro using dedicated optical system and software. The theoretical Point Spread Function along the optical axis, computed for several wavelengths, showed that for each wavelength, the IOL produces two main foci surrounded by numerous secondary foci that partially overlap each other for different wavelengths. The result is that both, the near focus and the far focus, have an extended depth of focus under polychromatic illumination. This theoretical prediction was confirmed experimentally by means of the Through-Focus Modulation Transfer Function, measured for different wavelengths. 000074805 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/DPI2015-71256-R 000074805 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000074805 590__ $$a2.776$$b2018 000074805 591__ $$aMULTIDISCIPLINARY SCIENCES$$b23 / 69 = 0.333$$c2018$$dQ2$$eT2 000074805 592__ $$a1.1$$b2018 000074805 593__ $$aAgricultural and Biological Sciences (miscellaneous)$$c2018$$dQ1 000074805 593__ $$aMedicine (miscellaneous)$$c2018$$dQ1 000074805 593__ $$aBiochemistry, Genetics and Molecular Biology (miscellaneous)$$c2018$$dQ1 000074805 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000074805 700__ $$aGarcía-Delpech, S. 000074805 700__ $$aUdaondo, P. 000074805 700__ $$aFerrando, V. 000074805 700__ $$aMonsoriu, J.A. 000074805 700__ $$aFurlan, W.D. 000074805 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica 000074805 773__ $$g13 (2018), 0200197 [11 pp]$$pPLoS One$$tPloS one$$x1932-6203 000074805 8564_ $$s1511169$$uhttps://zaguan.unizar.es/record/74805/files/texto_completo.pdf$$yVersión publicada 000074805 8564_ $$s103389$$uhttps://zaguan.unizar.es/record/74805/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000074805 909CO $$ooai:zaguan.unizar.es:74805$$particulos$$pdriver 000074805 951__ $$a2020-01-17-21:44:38 000074805 980__ $$aARTICLE