000075735 001__ 75735
000075735 005__ 20200729203741.0
000075735 0247_ $$2doi$$a10.1080/02713683.2017.1387272
000075735 0248_ $$2sideral$$a103914
000075735 037__ $$aART-2017-103914
000075735 041__ $$aeng
000075735 100__ $$0(orcid)0000-0002-6134-8698$$aSierra, M.$$uUniversidad de Zaragoza
000075735 245__ $$aEffect of cryopreserved amniotic membrane on the mechanical properties of skeletal muscle after strabismus surgery in rabbits
000075735 260__ $$c2017
000075735 5060_ $$aAccess copy available to the general public$$fUnrestricted
000075735 5203_ $$aPurpose: To study the functional recovery of the superior rectus muscle (SRM) after its partial resection in a rabbit model with and without cryopreserved amniotic membrane (AM).
Material and methods: Resection of the right and left SRMs of 30 rabbits was performed. On the left eyes, a single sheet of equine cryopreserved AM was placed covering the muscle edge sutured. Active and passive mechanical properties of muscles operated with and without AM were monitored over time at 30 (n = 10), 60 (n = 10), and 90 (n = 10) days after surgery. Muscle samples were extracted and electrically stimulated to register the force exerted by the samples, characterizing its active behavior. They were, then, subjected to stretching test to obtain its resistance to deformation, known as passive behavior. Moreover, right and left eyes of a control group (n = 5) were equally subjected to active and passive tests to characterize the physiological behavior of SRM muscles.
Results: On active function examination, statistically significant differences were documented between the following: control vs AM and no AM at 30 days (p = 0.002 and p = 0.04, respectively). All other comparisons were insignificant (p > 0.05). On passive function analysis, significant differences were only found between control vs. no AM at 30 days (p = 0.004) and between AM vs. no AM at 30 days (p = 0.002). Indeed, muscle operated without AM did not recover a normal passive function until 60 days after surgery.
Conclusion: Cryopreserved AM is effective in accelerating recovery of SRM passive function in rabbits. Nevertheless, AM produced no significant effect on recovery of SRM active function.¿
000075735 536__ $$9info:eu-repo/grantAgreement/ES/DGA/T88$$9info:eu-repo/grantAgreement/ES/MINECO/DPI2014-54981-R$$9info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84047-R
000075735 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000075735 590__ $$a2.12$$b2017
000075735 591__ $$aOPHTHALMOLOGY$$b27 / 59 = 0.458$$c2017$$dQ2$$eT2
000075735 592__ $$a0.956$$b2017
000075735 593__ $$aOphthalmology$$c2017$$dQ2
000075735 593__ $$aSensory Systems$$c2017$$dQ3
000075735 593__ $$aCellular and Molecular Neuroscience$$c2017$$dQ3
000075735 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000075735 700__ $$0(orcid)0000-0003-2770-4617$$aOrtillés, A.$$uUniversidad de Zaragoza
000075735 700__ $$0(orcid)0000-0001-5981-5448$$aMiana-Mena, F.J.$$uUniversidad de Zaragoza
000075735 700__ $$0(orcid)0000-0002-6870-0594$$aGrasa, J.$$uUniversidad de Zaragoza
000075735 700__ $$0(orcid)0000-0001-9713-1813$$aCalvo, B.$$uUniversidad de Zaragoza
000075735 7102_ $$11005$$2410$$aUniversidad de Zaragoza$$bDpto. Farmacología y Fisiolog.$$cÁrea Fisiología
000075735 7102_ $$11005$$2315$$aUniversidad de Zaragoza$$bDpto. Farmacología y Fisiolog.$$cÁrea Farmacología
000075735 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est.
000075735 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000075735 773__ $$g43, 2 (2017), 193-199$$pCurr. eye res.$$tCURRENT EYE RESEARCH$$x0271-3683
000075735 8564_ $$s313412$$uhttps://zaguan.unizar.es/record/75735/files/texto_completo.pdf$$yPostprint
000075735 8564_ $$s29591$$uhttps://zaguan.unizar.es/record/75735/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000075735 909CO $$ooai:zaguan.unizar.es:75735$$particulos$$pdriver
000075735 951__ $$a2020-07-29-20:20:07
000075735 980__ $$aARTICLE