La serotonina y los dos cerebros: Directora de orquesta de la fisiología intestinal y del estado de ánimo papel en el síndrome del intestino irritable
Sebastián Domingo, J.J. (Universidad de Zaragoza) ; Sebastián Sánchez, B.
Resumen: La serotonina, o 5-HT, también denominada enteramina o amina intestinal, es el neurotransmisor principal en el llamado segundo cerebro, el Sistema Nervioso Entérico, y uno de los más importantes en el Sistema Nervioso Central: el primer cerebro o cerebro propiamente dicho. Tener en mente sus funciones y su metabolismo, reconocer los síntomas derivados de su déficit funcional y saber cómo y cuándo aumentar su actividad, ya sea por métodos farmacológicos o no farmacológicos, nos ayudará a entender lo que está pasando en las “tripas” y en las emociones de nuestros pacientes, y, por tanto, a poder mejorar sus síntomas y su calidad de vida. En el artículo, se revisan los conocimientos actuales sobre el papel de aquella en la fisiología intestinal y en el estado de ánimo, así como la implicación de su transportador, el SERT, en la fisiopatología del Síndrome del Intestino Irritable, condición en la que se están utilizando, con aceptables resultados, los Inhibidores Selectivos de la Recaptación de Serotonina. Finalmente, se refieren diferentes formas de elevar los niveles de serotonina de forma no farmacológica (con la dieta, el ejercicio físico y la meditación o Mindfulness), en línea con la Medicina Naturista, en un intento de mejorar con ello algunos de los síntomas del Síndrome del Intestino Irritable.
Serotonin, or 5-HT, also known to as enteroamine or intestinal amine, is the main neurotransmitter in the second brain (i.e. the Enteric Nervous System) and one of the most important in the first brain: the Central Nervous System. Keeping in mind its functions and metabolism, recognizing its deficit and knowing how to increase its activity will help us understand what happens in the gut and emotions of our patients and, therefore, be able to improve their symptoms and quality of life. In this article, we review current knowledge about its role in intestinal physiology and mood, as well as the involvement of its transporter, the SERT, in the pathophysiology of irritable bowel syndrome, a condition in which Selective Serotonin Reuptake Inhibitors (SSRIs) are being used with acceptable results. Finally, we review different ways for raising serotonin levels in a non- pharmacological way (e.g. diet, physical exercise and meditation or Mindfulness) in line with Naturist Medicine, in an attempt to improve some of the symptoms of irritable bowel syndrome.
Idioma: Español
Año: 2018
Publicado en: Medicina naturista 12, 2 (2018), 11-17
ISSN: 1576-3080
Originalmente disponible en: Texto completo de la revista
Factor impacto SCIMAGO: 0.194 - Chiropractics (Q3) - Physical Therapy, Sports Therapy and Rehabilitation (Q3) - Complementary and Alternative Medicine (Q3)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2020-01-17-21:44:22)
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Serotonin, or 5-HT, also known to as enteroamine or intestinal amine, is the main neurotransmitter in the second brain (i.e. the Enteric Nervous System) and one of the most important in the first brain: the Central Nervous System. Keeping in mind its functions and metabolism, recognizing its deficit and knowing how to increase its activity will help us understand what happens in the gut and emotions of our patients and, therefore, be able to improve their symptoms and quality of life. In this article, we review current knowledge about its role in intestinal physiology and mood, as well as the involvement of its transporter, the SERT, in the pathophysiology of irritable bowel syndrome, a condition in which Selective Serotonin Reuptake Inhibitors (SSRIs) are being used with acceptable results. Finally, we review different ways for raising serotonin levels in a non- pharmacological way (e.g. diet, physical exercise and meditation or Mindfulness) in line with Naturist Medicine, in an attempt to improve some of the symptoms of irritable bowel syndrome.
Idioma: Español
Año: 2018
Publicado en: Medicina naturista 12, 2 (2018), 11-17
ISSN: 1576-3080
Originalmente disponible en: Texto completo de la revista
Factor impacto SCIMAGO: 0.194 - Chiropractics (Q3) - Physical Therapy, Sports Therapy and Rehabilitation (Q3) - Complementary and Alternative Medicine (Q3)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2020-01-17-21:44:22)
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Record created 2018-11-13, last modified 2020-01-17