Synthesis of cis-hydrindan-2, 4-diones bearing an all-carbon quaternary center by a Danheiser annulation

Saborit, G.V. ; Cativiela, C. (Universidad de Zaragoza) ; Jimenez, A.I. (Universidad de Zaragoza) ; Bonjoch, J. ; Bradshaw, B.

Resumen: A straightforward synthetic entry to functionalized hydrindane compounds based on a rapid assembly of the core nucleus by a Danheiser cycloaddition is reported. Valuable bicyclic building blocks containing the fused five and six-membered carbocyclic ring system can be achieved in only four steps from a simple acyclic beta-keto ester.

Idioma: Inglés

DOI: 10.3762/bjoc.14.237

Año: 2018

Publicado en: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY 14 (2018), 2597-2601
ISSN: 1860-5397

Factor impacto JCR: 2.595 (2018)

Categ. JCR: CHEMISTRY, ORGANIC rank: 20 / 57 = 0.351 (2018) - Q2 - T2

Factor impacto SCIMAGO: 0.821 - Organic Chemistry (Q2)

Financiación: info:eu-repo/grantAgreement/ES/DGA/E19-17R
Financiación: info:eu-repo/grantAgreement/ES/MINECO/CTQ2013-40855-R
Financiación: info:eu-repo/grantAgreement/ES/MINECO/CTQ2016-41338-P

Tipo y forma: Article (Published version)

Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)