Production, characterization and testing of antibacterial PVA membranes loaded with HA-Ag3PO4 nanoparticles, produced by SC-CO2 phase inversion

Baldino, L. ; Aragón, J. ; Mendoza, G. (Universidad de Zaragoza) ; Irusta, S. (Universidad de Zaragoza) ; Cardea, S. ; Reverchon, E.

Resumen: BACKGROUND: Silver-loaded hydroxyapatite nanoparticles were incorporated into poly(vinyl alcohol) (PVA) membranes obtained by supercritical CO2 (SC-CO2) assisted phase inversion. Ag3PO4 crystals of 2.2 ± 0.6 nm were dispersed in synthesized needle-like hydroxyapatite nanoparticles (20 × 65 nm) and were uniformly deposited on the internal surfaces of the PVA membranes. Operative conditions to produce membranes by SC-CO2, PVA concentration and the effect on membrane porosity and morphology were studied. RESULTS: Solutions at 20% w/w PVA produced membranes with cellular morphology and nanoporous walls, whereas 30% and 50% w/w solutions produced nanostructured membranes. Silver ions were released from PVA membranes mainly by diffusion according to the Peppas–Sahlin model. Membranes obtained at 20% w/w PVA showed a significant E. coli inhibition at an Ag concentration of 9 ppm, reaching the minimal inhibitory concentration (MIC) and improving the bactericidal activity of the nanoparticles. CONCLUSION: A concentration of Ag3PO4 crystals of about 22 ppm was calculated as being capable of completely destroying these bacteria, reaching the minimum bactericidal concentration (MBC).

Idioma: Inglés

DOI: 10.1002/jctb.5749

Año: 2019

Publicado en: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 94, 1 (2019), 98-108
ISSN: 0268-2575

Factor impacto JCR: 2.75 (2019)

Categ. JCR: BIOTECHNOLOGY & APPLIED MICROBIOLOGY rank: 72 / 156 = 0.462 (2019) - Q2 - T2
Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 84 / 177 = 0.475 (2019) - Q2 - T2
Categ. JCR: ENGINEERING, CHEMICAL rank: 60 / 143 = 0.42 (2019) - Q2 - T2
Categ. JCR: ENGINEERING, ENVIRONMENTAL rank: 28 / 53 = 0.528 (2019) - Q3 - T2

Factor impacto SCIMAGO: 0.661 - Inorganic Chemistry (Q1) - Chemical Engineering (miscellaneous) (Q1) - Fuel Technology (Q2) - Waste Management and Disposal (Q2) - Organic Chemistry (Q2) - Pollution (Q2) - Renewable Energy, Sustainability and the Environment (Q2) - Biotechnology (Q2)

Tipo y forma: Artículo (PostPrint)

Área (Departamento): Área Ingeniería Química (Dpto. Ing.Quím.Tecnol.Med.Amb.)
Área (Departamento): Área Tecnologi. Medio Ambiente (Dpto. Ing.Quím.Tecnol.Med.Amb.)