Simultaneous extraction and analysis of preservatives and artificial sweeteners in juices by salting out liquid-liquid extraction method prior to ultra-high performance liquid chromatography

Tighrine, A. ; Amir, Y. ; Alfaro, P. (Universidad de Zaragoza) ; Mamou, M. ; Nerín, C. (Universidad de Zaragoza)

Resumen: A novel and fast salting out liquid-liquid extraction method was developed for simultaneous determination of food additives with different polarities in juices. Chromatographic separation was achieved in less than 6 min using Acquity UPLC BEH C 18 (100 mm × 2.1 mm d.i. × 1.7 µm) column with ammonium acetate with 0.01% of trifluoroacetic acid as eluent A and acetonitrile as eluent B at a flow rate of 0.2 mL min-1. The main factors affecting the extraction efficiency were optimized. The method was validated applying accuracy profile based on total error. The extraction recoveries ranged from 84.97 to 122%. Relative standard deviation ranged from 1.24 to 7.99% for intraday assay and from 1.69 to 9.16% for intermediate precision. The limits of detection for five food additives were from 0.3 to 1.42 µg mL-1. The method was successfully applied to 47 samples of juices from nine brands.

Idioma: Inglés

DOI: 10.1016/j.foodchem.2018.10.107

Año: 2019

Publicado en: Food Chemistry 277 (2019), 586-594
ISSN: 0308-8146

Factor impacto JCR: 6.306 (2019)

Categ. JCR: CHEMISTRY, APPLIED rank: 5 / 71 = 0.07 (2019) - Q1 - T1
Categ. JCR: NUTRITION & DIETETICS rank: 10 / 89 = 0.112 (2019) - Q1 - T1
Categ. JCR: FOOD SCIENCE & TECHNOLOGY rank: 6 / 139 = 0.043 (2019) - Q1 - T1

Factor impacto SCIMAGO: 1.775 - Analytical Chemistry (Q1) - Medicine (miscellaneous) (Q1) - Food Science (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/T53-17R

Tipo y forma: Artículo (PostPrint)

Área (Departamento): Área Química Analítica (Dpto. Química Analítica)
Área (Departamento): Proy. investigación HVA (Dpto. Química Analítica)