En Route to Chiral-at-Metal Ruthenium Complexes Containing Tripodal Tetradentate Ligands

Téllez, Juan ; Méndez, Isabel ; Viguri, Fernando (Universidad de Zaragoza) ; Rodríguez, Ricardo (Universidad de Zaragoza) ; Lahoz, Ferenando J. (Universidad de Zaragoza) ; García-Orduña, Pilar (Universidad de Zaragoza) ; Carmona, Daniel

Resumen: Synthetic routes for ruthenium(II) complexes bearing the {Ru(¿4C, N, N', P-L)} fragment (L = tripodal tetradentate ligand) are explored. Tripodal ligands LH1-LH3 diastereoselectively react with the dimer [{(Cy)RuCl}2(µ-Cl)2] (Cy = ¿6-p-MeC6H4iPr), affording the p-cymene compounds [(Cy)Ru(¿3N, N', P-LH)][SbF6] (1-3). Refluxing complexes 1-3 in MeCN gives [Ru(¿3N, N', P-LH)(NCMe)3][SbF6]2 (4a-6a). In refluxing MeOH, isomers 4a-6a evolve to the corresponding mer complexes 4c-6c. Reaction of [RuCl2(PPh3)3] with LH1 affords [RuCl2(PPh3)(¿3N, N', P-LH1)] (7) as only one isomer. [RuClH(CO)(PPh3)3] reacts with ligands LH1-LH3 to give [RuH(CO)(PPh3)(¿3N, N', P-LH)]Cl (8-10). Complexes 8-10 were isolated as a mixture of only two diastereomers as pairs of enantiomers. Refluxing suspensions of complexes 8-10 in 2-ethoxyethanol afforded the corresponding metalated complexes [RuCl(CO)(¿4C, N, N', P-L)] (11-13), in which the tripodal ligands L1-L3 act as tetradentate ligands. Only one stereoisomer was detected for complexes 11 and 13, but metalation at the C-2 or C-6 carbons gave a mixture of two isomers for complex 12. The new complexes have been characterized by analytical and spectroscopic means and by the determination of the crystal structures of the complexes 1, 2, 5c, 10a, 11a, 12a, b, and 13a by X-ray diffractometry.

Idioma: Inglés

DOI: 10.1021/acs.organomet.8b00180

Año: 2018

Publicado en: Organometallics 37, 20 (2018), 3450-3464
ISSN: 0276-7333

Factor impacto JCR: 4.1 (2018)

Categ. JCR: CHEMISTRY, ORGANIC rank: 11 / 57 = 0.193 (2018) - Q1 - T1
Categ. JCR: CHEMISTRY, INORGANIC & NUCLEAR rank: 5 / 45 = 0.111 (2018) - Q1 - T1

Factor impacto SCIMAGO: 1.473 - Inorganic Chemistry (Q1) - Physical and Theoretical Chemistry (Q1) - Organic Chemistry (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MINECO/CTQ2015-66079-P
Financiación: info:eu-repo/grantAgreement/ES/MINECO/RYC-2013-13800

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Química Inorgánica (Dpto. Química Inorgánica)