000089552 001__ 89552
000089552 005__ 20231127095530.0
000089552 0247_ $$2doi$$a10.1016/j.aca.2019.05.077
000089552 0248_ $$2sideral$$a112594
000089552 037__ $$aART-2019-112594
000089552 041__ $$aeng
000089552 100__ $$0(orcid)0000-0002-1856-2058$$aBolea-Fernández, Eduardo
000089552 245__ $$aOn the effect of using collision/reaction cell (CRC) technology in single-particle ICP-mass spectrometry (SP-ICP-MS)
000089552 260__ $$c2019
000089552 5060_ $$aAccess copy available to the general public$$fUnrestricted
000089552 5203_ $$aIn this work, the effects of using collision/reaction cell (CRC) technology in quadrupole-based ICP-MS (ICP-QMS) instrumentation operated in single-particle (SP) mode have been assessed. The influence of (i) various CRC gases, (ii) gas flow rates, (iii) nanoparticle (NP) sizes and (iv) NP types was evaluated using Ag, Au and Pt NPs with both a traditional ICP-QMS instrument and a tandem ICP-mass spectrometer. It has been shown that using CRC technology brings about a significant increase in the NP signal peak width (from 0.5 up to 6¿ms). This effect is more prominent for a heavier gas (e.g., NH3) than for a lighter one (e.g., H2 or He). At a higher gas flow rate and/or for larger particle sizes >100¿nm), the NP signal duration was prolonged to a larger extent. This effect of using CRC technology has been further demonstrated by characterizing custom-made 50 and 200¿nm Fe3O4 NPs (originally strongly affected by the occurrence of spectral overlap) using different CRC approaches (H2 on-mass and NH3 mass-shift). The use of NH3 (monitoring of Fe as the Fe(NH3)2+ reaction product ion at m/z¿=¿90 amu) induces a significant peak broadening compared to that observed when using H2 (6.10¿±¿1.60 vs. 0.94¿±¿0.49¿ms). This extension of transit time can most likely be attributed to the collisions/interactions of the ion cloud generated by a single NP event with the CRC gas and it even precludes 50¿nm Fe3O4 NPs to be detected when using the NH3 mass-shift approach. Based on these results, the influence of a longer peak width on the accuracy of SP-ICP-MS measurement data (NP size, particle number density and mass concentration) must be taken into account when using CRC technology as a means to overcome spectral overlap. To mitigate the potential detrimental effect of using CRC technology in the characterization of NPs via SP-ICP-MS(/MS), the use of light gases and low gas flow rates is recommended.
000089552 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/CTQ2015-64684-P$$9info:eu-repo/grantAgreement/ES/MINECO-FEDER/PGC2018-093753-B-I00
000089552 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000089552 590__ $$a5.977$$b2019
000089552 591__ $$aCHEMISTRY, ANALYTICAL$$b10 / 86 = 0.116$$c2019$$dQ1$$eT1
000089552 592__ $$a1.414$$b2019
000089552 593__ $$aAnalytical Chemistry$$c2019$$dQ1
000089552 593__ $$aSpectroscopy$$c2019$$dQ1
000089552 593__ $$aEnvironmental Chemistry$$c2019$$dQ1
000089552 593__ $$aBiochemistry$$c2019$$dQ1
000089552 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000089552 700__ $$aLeite, Diego
000089552 700__ $$aRua-Ibarz, Ana
000089552 700__ $$aLiu, Tong
000089552 700__ $$aWoods, Glenn
000089552 700__ $$0(orcid)0000-0002-3916-9992$$aAramendia Marzo, Maite$$uUniversidad de Zaragoza
000089552 700__ $$0(orcid)0000-0002-7450-8769$$aResano, Martín$$uUniversidad de Zaragoza
000089552 700__ $$aVanhaecke, Frank
000089552 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000089552 773__ $$g1077 (2019), 95-106$$pAnal. chim. acta$$tAnalytica Chimica Acta$$x0003-2670
000089552 8564_ $$s1136258$$uhttps://zaguan.unizar.es/record/89552/files/texto_completo.pdf$$yPostprint
000089552 8564_ $$s309943$$uhttps://zaguan.unizar.es/record/89552/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000089552 909CO $$ooai:zaguan.unizar.es:89552$$particulos$$pdriver
000089552 951__ $$a2023-11-27-09:46:37
000089552 980__ $$aARTICLE