The Harvey-Bradshaw Index Adapted to a Mobile Application Compared with In-Clinic Assessment: The MediCrohn Study
Echarri, A ; Vera, I ; Ollero, V ; Arajol, C ; Riestra, S ; Robledo, P ; Calvo, M ; Gallego, F ; Ceballos, D ; Castro, B ; Aguas, M ; García-López, Santiago (Universidad de Zaragoza) ; Mar?n-Jim?nez, I ; Chaparro, M ; Mesonero, P ; Guerra, I ; Guardiola, J ; Nos, P ; Mu?iz, J
Resumen: Objectives: Mobile apps are useful tools in e-health and self-management strategies in disease monitoring. We evaluated the Harvey-Bradshaw index (HBI) mobile app self-administered by the patient to see if its results agreed with HBI in-clinic assessed by a physician.
Methods: Patients were enrolled in a 4-month prospective study with clinical assessments at months 1 and 4. Patients completed mobile app HBI and within 48 h, HBI was performed by a physician (gold standard). HBI scores characterized Crohn''s disease (CD) as remission <5 or active >= 5. We determined agreement per item and total HBI score and intraclass correlation coefficients (ICCs). Bland-Altman plot was performed. HBI changes in disease activity from month 1 to month 4 were determined. Results: A total of 219 patients were enrolled. All scheduled assessments (385 pairs of the HBI questionnaire) showed a high percentage of agreement for remission/activity (92.4%, kappa = 0.796), positive predictive value (PPV) for remission of 98.2%, and negative predictive value of 76.7%. High agreement was also found at month 1 (93.15%, kappa = 0.82) and month 4 (91.5%, kappa = 0.75). Bland-Altman plot was more uniform when the HBI mean values were <5 (remission). ICC values were 0.82, 0.897, and 0.879 in all scheduled assessments, 1 and 4 months, respectively.
Conclusions: We found a high percentage of agreement between patients' self-administered mobile app HBI and in-clinic physician assessment to detect CD activity with a remarkably high PPV for remission. The mobile app HBI might allow a strict control of inflammation by remote monitoring and flexible follow-up of CD patients. Reduction of sanitary costs could be possible.
Idioma: Inglés
DOI: 10.1089/tmj.2018.0264
Año: 2020
Publicado en: TELEMEDICINE AND E-HEALTH 26, 1 (2020), 78-86
ISSN: 1530-5627
Factor impacto JCR: 3.536 (2020)
Categ. JCR: HEALTH CARE SCIENCES & SERVICES rank: 36 / 108 = 0.333 (2020) - Q2 - T2
Factor impacto SCIMAGO: 0.95 - Health Informatics (Q1) - Medicine (miscellaneous) (Q1) - Health Information Management (Q1)
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/2015–2017
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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Methods: Patients were enrolled in a 4-month prospective study with clinical assessments at months 1 and 4. Patients completed mobile app HBI and within 48 h, HBI was performed by a physician (gold standard). HBI scores characterized Crohn''s disease (CD) as remission <5 or active >= 5. We determined agreement per item and total HBI score and intraclass correlation coefficients (ICCs). Bland-Altman plot was performed. HBI changes in disease activity from month 1 to month 4 were determined. Results: A total of 219 patients were enrolled. All scheduled assessments (385 pairs of the HBI questionnaire) showed a high percentage of agreement for remission/activity (92.4%, kappa = 0.796), positive predictive value (PPV) for remission of 98.2%, and negative predictive value of 76.7%. High agreement was also found at month 1 (93.15%, kappa = 0.82) and month 4 (91.5%, kappa = 0.75). Bland-Altman plot was more uniform when the HBI mean values were <5 (remission). ICC values were 0.82, 0.897, and 0.879 in all scheduled assessments, 1 and 4 months, respectively.
Conclusions: We found a high percentage of agreement between patients' self-administered mobile app HBI and in-clinic physician assessment to detect CD activity with a remarkably high PPV for remission. The mobile app HBI might allow a strict control of inflammation by remote monitoring and flexible follow-up of CD patients. Reduction of sanitary costs could be possible.
Idioma: Inglés
DOI: 10.1089/tmj.2018.0264
Año: 2020
Publicado en: TELEMEDICINE AND E-HEALTH 26, 1 (2020), 78-86
ISSN: 1530-5627
Factor impacto JCR: 3.536 (2020)
Categ. JCR: HEALTH CARE SCIENCES & SERVICES rank: 36 / 108 = 0.333 (2020) - Q2 - T2
Factor impacto SCIMAGO: 0.95 - Health Informatics (Q1) - Medicine (miscellaneous) (Q1) - Health Information Management (Q1)
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/2015–2017
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. Exportado de SIDERAL (2021-09-02-08:46:09)
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Record created 2020-10-22, last modified 2021-09-02