The evolving microbiome from pregnancy to early infancy: A comprehensive review

Mesa, María D. ; Loureiro, Begoña ; Iglesia, Iris ; Fernandez Gonzalez, Sergi ; Llurba Olivé, Elisa ; García Algar, Oscar ; Solana, María J. ; Cabero Perez, Mª J. ; Sainz, Talia ; Martinez, Leopoldo ; Escuder-Vieco, Diana ; Parra-Llorca, Anna ; Sánchez-Campillo, María ; Rodriguez Martinez, Gerardo (Universidad de Zaragoza) ; Gómez Roig, Dolores ; Perez Gruz, Myriam ; Andreu-Fernández, Vicente ; Clotet, Jordi ; Sailer, Sebastian ; Iglesias-Platas, Isabel ; López-Herce, Jesús ; Aras, Rosa ; Pallás-Alonso, Carmen ; de Pipaon, Miguel S. ; Vento, Máximo ; Gormaz, María ; Larqué Daza, Elvira ; Calvo, Cristina ; Cabañas, Fernando

Resumen: Pregnancy induces a number of immunological, hormonal, and metabolic changes that are necessary for the mother to adapt her body to this new physiological situation. The microbiome of the mother, the placenta and the fetus influence the fetus growth and undoubtedly plays a major role in the adequate development of the newborn infant. Hence, the microbiome modulates the inflammatory mechanisms related to physiological and pathological processes that are involved in the perinatal progress through different mechanisms. The present review summarizes the actual knowledge related to physiological changes in the microbiota occurring in the mother, the fetus, and the child, both during neonatal period and beyond. In addition, we approach some specific pathological situations during the perinatal periods, as well as the influence of the type of delivery and feeding.

Idioma: Inglés

DOI: 10.3390/nu12010133

Año: 2020

Publicado en: Nutrients 12, 1 (2020), 133 [21 pp.]
ISSN: 2072-6643

Factor impacto JCR: 5.717 (2020)

Categ. JCR: NUTRITION & DIETETICS rank: 17 / 88 = 0.193 (2020) - Q1 - T1

Factor impacto SCIMAGO: 1.417 - Nutrition and Dietetics (Q1) - Food Science (Q1)

Financiación: info:eu-repo/grantAgreement/ES/ISCIII/CM18-00165
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/JR16-00021
Financiación: info:eu-repo/grantAgreement/ES/RETICS-ISCIII-ERDF/RD16-0022-0015

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Pediatría (Dpto. Microb.Ped.Radio.Sal.Pú.)