000096092 001__ 96092
000096092 005__ 20210902121813.0
000096092 0247_ $$2doi$$a10.1093/ecco-jcc/jjz180
000096092 0248_ $$2sideral$$a118291
000096092 037__ $$aART-2020-118291
000096092 041__ $$aeng
000096092 100__ $$aTorres, J.
000096092 245__ $$aECCO guidelines on therapeutics in Crohn's disease: Medical treatment
000096092 260__ $$c2020
000096092 5060_ $$aAccess copy available to the general public$$fUnrestricted
000096092 5203_ $$aCrohn’s disease [CD] is a chronic inflammatory bowel disease [IBD] that can result in progressive bowel damage and disability1. CD can affect individuals of any age, from children to the elderly, 2, 3 and may cause significant morbidity and impact on quality of life. Up to one-third of patients present with complicated behaviour [strictures, fistula, or abscesses] at diagnosis4. Most patients over time will develop a complication, with roughly 50% of patients requiring surgery within 10 years of diagnosis5-7. As the precise aetiology of CD remains unknown, a curative therapy is not yet available8. Several agents are available for the medical treatment of CD. Medical agents include mesalazine [5-ASA], locally active steroids [such as budesonide], systemic steroids, thiopurines such as azathioprine [AZA] and mercaptopurine [MP], methotrexate [MTX], and biological therapies [such as anti-TNF, anti-integrins, and anti-IL12/23].
The European Crohn’s and Colitis Organisation [ECCO] produces and regularly updates several guidelines aimed at providing evidence-based guidance on critical aspects of IBD care to all healthcare professionals who manage patients with IBD. To provide high-quality evidence-based recommendations on medical and surgical treatment in CD, ECCO decided to develop these guidelines by adopting the GRADE [Grading of Recommendations Assessment, Development, and Evaluation] approach9. GRADE is a systematic process for developing guidelines that addresses how to frame the healthcare questions, summarize the evidence, ..
000096092 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000096092 590__ $$a9.071$$b2020
000096092 591__ $$aGASTROENTEROLOGY & HEPATOLOGY$$b14 / 92 = 0.152$$c2020$$dQ1$$eT1
000096092 592__ $$a3.277$$b2020
000096092 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000096092 593__ $$aGastroenterology$$c2020$$dQ1
000096092 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion
000096092 700__ $$aBonovas, S.
000096092 700__ $$aDoherty, G.
000096092 700__ $$aKucharzik, T.
000096092 700__ $$aGisbert, J.P.
000096092 700__ $$aRaine, T.
000096092 700__ $$aAdamina, M.
000096092 700__ $$aArmuzzi, A.
000096092 700__ $$aBachmann, O.
000096092 700__ $$aBager, P.
000096092 700__ $$aBiancone, L.
000096092 700__ $$aBokemeyer, B.
000096092 700__ $$aBossuyt, P.
000096092 700__ $$aBurisch, J.
000096092 700__ $$aCollins, P.
000096092 700__ $$aEl-Hussuna, A.
000096092 700__ $$aEllul, P.
000096092 700__ $$aFrei-Lanter, C.
000096092 700__ $$aFurfaro, F.
000096092 700__ $$aGingert, C.
000096092 700__ $$aGionchetti, P.
000096092 700__ $$0(orcid)0000-0003-0076-3529$$aGomollon, F.$$uUniversidad de Zaragoza
000096092 700__ $$aGonzález-Lorenzo, M.
000096092 700__ $$aGordon, H.
000096092 700__ $$aHlavaty, T.
000096092 700__ $$aJuillerat, P.
000096092 700__ $$aKatsanos, K.
000096092 700__ $$aKopylov, U.
000096092 700__ $$aKrustins, E.
000096092 700__ $$aLytras, T.
000096092 700__ $$aMaaser, C.
000096092 700__ $$aMagro, F.
000096092 700__ $$aKenneth Marshall, J.
000096092 700__ $$aMyrelid, P.
000096092 700__ $$aPellino, G.
000096092 700__ $$aRosa, I.
000096092 700__ $$aSabino, J.
000096092 700__ $$aSavarino, E.
000096092 700__ $$aSpinelli, A.
000096092 700__ $$aStassen, L.
000096092 700__ $$aUzzan, M.
000096092 700__ $$aVavricka, S.
000096092 700__ $$aVerstockt, B.
000096092 700__ $$aWarusavitarne, J.
000096092 700__ $$aZmora, O.
000096092 700__ $$aFiorino, G.
000096092 700__ $$aon, behalf, of, the, European, Crohn''s, and, Colitis, Organisation, [ECCO]
000096092 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000096092 773__ $$g14, 1 (2020), 4-22$$pJ. Crohns Colitis$$tJournal of Crohn's & colitis$$x1873-9946
000096092 8564_ $$s607630$$uhttps://zaguan.unizar.es/record/96092/files/texto_completo.pdf$$yPostprint
000096092 8564_ $$s664411$$uhttps://zaguan.unizar.es/record/96092/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000096092 909CO $$ooai:zaguan.unizar.es:96092$$particulos$$pdriver
000096092 951__ $$a2021-09-02-10:02:37
000096092 980__ $$aARTICLE