Simple Sonochemical Method to Optimize the Heating Efficiency of Magnetic Nanoparticles for Magnetic Fluid Hyperthermia

Fuentes-García, J.A. ; Carvalho Alavarse, A. ; Moreno Maldonado, A.C. (Universidad de Zaragoza) ; Toro-Córdova, A. (Universidad de Zaragoza) ; Ibarra, M.R. (Universidad de Zaragoza) ; Goya, G.F. (Universidad de Zaragoza)

Resumen: We developed a fast, single-step sonochemical strategy for the green manufacturing of magnetite (Fe3O4) magnetic nanoparticles (MNPs), using iron sulfate (FeSO4) as the sole source of iron and sodium hydroxide (Na(OH)) as the reducing agent in an aqueous medium. The designed methodology reduces the environmental impact of toxic chemical compounds and minimizes the infrastructure requirements and reaction times down to minutes. The Na(OH) concentration has been varied to optimize the final size and magnetic properties of the MNPs and to minimize the amount of corrosive byproducts of the reaction. The change in the starting FeSO4concentration (from 5.4 to 43.1 mM) changed the particle sizes from (20 ± 3) to (58 ± 8) nm. These magnetite MNPs are promising for biomedical applications due to their negative surface charge, good heating properties (˜324 ± 2 W/g), and low cytotoxic effects. These results indicate the potential of this controlled, easy, and rapid ultrasonic irradiation method to prepare nanomaterials with enhanced properties and good potential for use as magnetic hyperthermia agents.

Idioma: Inglés

DOI: 10.1021/acsomega.0c02212

Año: 2020

Publicado en: ACS OMEGA 5, 41 (2020), 26357-26364
ISSN: 2470-1343

Factor impacto JCR: 3.512 (2020)

Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 78 / 178 = 0.438 (2020) - Q2 - T2

Factor impacto SCIMAGO: 0.779 - Chemistry (miscellaneous) (Q1) - Chemical Engineering (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/E26
Financiación: info:eu-repo/grantAgreement/ES/MCIU/MAT2016-78201-P
Financiación: info:eu-repo/grantAgreement/ES/MCIU/RTC-2017-6620-1

Tipo y forma: Article (Published version)

Área (Departamento): Área Física Materia Condensada (Dpto. Física Materia Condensa.)