Coagulation Parameters: An Efficient Measure for Predicting the Prognosis and Clinical Management of Patients with COVID-19
Quintana-Diaz, M. ; Andres-Esteban, E.M. ; Ramirez-Cervantes, K.L. ; Olivan-Blazquez, B. (Universidad de Zaragoza) ; Juarez-Vela, R. ; Gea-Caballero, V.
Resumen: Background. COVID-19 is an ongoing global pandemic. Since the detection of the first cases of coronavirus disease 2019 (COVID-19) in Wuhan, China, the current pandemic has affected more than 25.3 million people worldwide. The aim of this study was to evaluate the relationship between coagulation abnormalities and prognosis in a cohort of patients with COVID-19.
Methods. We performed a retrospective cohort study of 3581 patients admitted to Hospital La Paz (Madrid, Spain) due to respiratory infection by severe acute respiratory syndrome coronavirus from the beginning of the current pandemic to 15 July 2020.
Results. Of the 3581 study patients, 48.94% were men, and 19.80% were healthcare workers. The median age was 62 years. Compared with the survivors, the non-survivors had lower prothrombin activity (82.5 (Interquartile range-IQR, 67-95) vs. 95.25 (IQR, 87-104) for non-survivors and survivors, respectively; p < 0.001), higher fibrinogen levels (748.5-IQR, 557-960) vs. 572.75 (IQR, 417-758; p < 0.001), and notably higher D-dimer levels (2329-IQR, 1086.12-5670.40) vs. 635.5 (IQR, 325.5-1194.8); p < 0.001).
Conclusions. The evaluation of coagulation parameters could be an efficient measure for predicting the prognosis and improving the clinical management of patients with COVID-19.
Idioma: Inglés
DOI: 10.3390/jcm9113482
Año: 2020
Publicado en: JOURNAL OF CLINICAL MEDICINE 9, 11 (2020), 3482 [11 pp]
ISSN: 2077-0383
Factor impacto JCR: 4.241 (2020)
Categ. JCR: MEDICINE, GENERAL & INTERNAL rank: 39 / 169 = 0.231 (2020) - Q1 - T1
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/COV20-00519
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Área Psicología Social (Dpto. Psicología y Sociología)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace.
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Methods. We performed a retrospective cohort study of 3581 patients admitted to Hospital La Paz (Madrid, Spain) due to respiratory infection by severe acute respiratory syndrome coronavirus from the beginning of the current pandemic to 15 July 2020.
Results. Of the 3581 study patients, 48.94% were men, and 19.80% were healthcare workers. The median age was 62 years. Compared with the survivors, the non-survivors had lower prothrombin activity (82.5 (Interquartile range-IQR, 67-95) vs. 95.25 (IQR, 87-104) for non-survivors and survivors, respectively; p < 0.001), higher fibrinogen levels (748.5-IQR, 557-960) vs. 572.75 (IQR, 417-758; p < 0.001), and notably higher D-dimer levels (2329-IQR, 1086.12-5670.40) vs. 635.5 (IQR, 325.5-1194.8); p < 0.001).
Conclusions. The evaluation of coagulation parameters could be an efficient measure for predicting the prognosis and improving the clinical management of patients with COVID-19.
Idioma: Inglés
DOI: 10.3390/jcm9113482
Año: 2020
Publicado en: JOURNAL OF CLINICAL MEDICINE 9, 11 (2020), 3482 [11 pp]
ISSN: 2077-0383
Factor impacto JCR: 4.241 (2020)
Categ. JCR: MEDICINE, GENERAL & INTERNAL rank: 39 / 169 = 0.231 (2020) - Q1 - T1
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/COV20-00519
Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Área Psicología Social (Dpto. Psicología y Sociología)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. Exportado de SIDERAL (2021-09-02-10:29:35)
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Artículos > Artículos por área > Psicología Social
Registro creado el 2021-01-19, última modificación el 2021-09-02