000098195 001__ 98195
000098195 005__ 20210902121850.0
000098195 0247_ $$2doi$$a10.3390/jcm9113482
000098195 0248_ $$2sideral$$a121546
000098195 037__ $$aART-2020-121546
000098195 041__ $$aeng
000098195 100__ $$aQuintana-Diaz, M.
000098195 245__ $$aCoagulation Parameters: An Efficient Measure for Predicting the Prognosis and Clinical Management of Patients with COVID-19
000098195 260__ $$c2020
000098195 5060_ $$aAccess copy available to the general public$$fUnrestricted
000098195 5203_ $$aBackground. COVID-19 is an ongoing global pandemic. Since the detection of the first cases of coronavirus disease 2019 (COVID-19) in Wuhan, China, the current pandemic has affected more than 25.3 million people worldwide. The aim of this study was to evaluate the relationship between coagulation abnormalities and prognosis in a cohort of patients with COVID-19.
Methods. We performed a retrospective cohort study of 3581 patients admitted to Hospital La Paz (Madrid, Spain) due to respiratory infection by severe acute respiratory syndrome coronavirus from the beginning of the current pandemic to 15 July 2020.
Results. Of the 3581 study patients, 48.94% were men, and 19.80% were healthcare workers. The median age was 62 years. Compared with the survivors, the non-survivors had lower prothrombin activity (82.5 (Interquartile range-IQR, 67-95) vs. 95.25 (IQR, 87-104) for non-survivors and survivors, respectively; p < 0.001), higher fibrinogen levels (748.5-IQR, 557-960) vs. 572.75 (IQR, 417-758; p < 0.001), and notably higher D-dimer levels (2329-IQR, 1086.12-5670.40) vs. 635.5 (IQR, 325.5-1194.8); p < 0.001).
Conclusions. The evaluation of coagulation parameters could be an efficient measure for predicting the prognosis and improving the clinical management of patients with COVID-19.
000098195 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/COV20-00519
000098195 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000098195 590__ $$a4.241$$b2020
000098195 591__ $$aMEDICINE, GENERAL & INTERNAL$$b39 / 169 = 0.231$$c2020$$dQ1$$eT1
000098195 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000098195 700__ $$aAndres-Esteban, E.M.
000098195 700__ $$aRamirez-Cervantes, K.L.
000098195 700__ $$0(orcid)0000-0001-6565-9699$$aOlivan-Blazquez, B.$$uUniversidad de Zaragoza
000098195 700__ $$aJuarez-Vela, R.
000098195 700__ $$aGea-Caballero, V.
000098195 7102_ $$14009$$2740$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Social
000098195 773__ $$g9, 11 (2020), 3482 [11 pp]$$pJ. clin.med.$$tJOURNAL OF CLINICAL MEDICINE$$x2077-0383
000098195 8564_ $$s448943$$uhttps://zaguan.unizar.es/record/98195/files/texto_completo.pdf$$yVersión publicada
000098195 8564_ $$s2471157$$uhttps://zaguan.unizar.es/record/98195/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000098195 909CO $$ooai:zaguan.unizar.es:98195$$particulos$$pdriver
000098195 951__ $$a2021-09-02-10:29:35
000098195 980__ $$aARTICLE