Primary endometrial carcinoma with signet-ring cells. A case report and review of the literature

Navarro Sierra, J. ; Espiau Romera, A. ; Narváez Salazar, M. ; Puente Luján, M.J. ; Eizaguirre Zarza, B. ; Baquedano Mainar, L.

Resumen: Endometrial adenocarcinoma with signet-ring cells is an infrequent histological type of carcinoma that usually corresponds to a metastasis of a primary carcinoma of another origin, mainly from the gastrointestinal tract or the breast. For this reason, in view of this histological finding, it is essential to carry out a thorough evaluation including mammography, gastroscopy, colonoscopy and thoracoabdominopelvic CT. To date, only six cases of primary endometrial carcinoma with signet-ring cells have been reported in the English literature. A 73-year-old patient was referred to the Gynecology Department with a 3-day history of postmenopausal bleeding. She was diagnosed with primary endometrial adenocarcinoma with signet-ring cells. The anatomopathological special features of the surgical specimen are presented, as well as the evolution of the patient, who remained asymptomatic and free of disease 28 months after surgery. A review of the literature is performed, emphasizing the peculiarities of this rare histological subtype. Despite the fact that primary endometrial carcinoma with signet-ring cells is an infrequent tumor, it must be considered in the differential diagnosis of malignant tumors of aforesaid origin. It is essential to carry out a correct and an extensive investigative study as well as an immunohistochemical analysis of the samples obtained for its confirmation diagnosis.

Idioma: Inglés

DOI: 10.31083/J.EJGO.2020.06.2185

Año: 2020

Publicado en: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 41, 6 (2020), 879-883
ISSN: 0392-2936

Factor impacto JCR: 0.196 (2020)

Categ. JCR: ONCOLOGY rank: 240 / 242 = 0.992 (2020) - Q4 - T3
Categ. JCR: OBSTETRICS & GYNECOLOGY rank: 81 / 83 = 0.976 (2020) - Q4 - T3

Factor impacto SCIMAGO: 0.15 - Oncology (Q4) - Obstetrics and Gynecology (Q4)

Tipo y forma: Article (Published version)