Non-Invasive Identification of Atrial Fibrillation Driver Location Using the 12-lead ECG: Pulmonary Vein Rotors vs. other Locations

Luongo, Giorgio ; Azzolin, Luca ; Martínez, Juan Pablo ; Laguna, Pablo ; Doessel, Olaf ; Loewe, Axel ; Sassi, Roberto ; Rivolta, Massimo Walter

Resumen: Atrial fibrillation (AF) is an irregular heart rhythm due to disorganized atrial electrical activity, often sustained by rotational drivers called rotors. In the present work, we sought to characterize and discriminate whether simulated single stable rotors are located in the pulmonary veins (PVs) or not, only by using non-invasive signals (i.e., the 12-lead ECG). Several features have been extracted from the signals, such as Hjort descriptors, recurrence quantification analysis (RQA), and principal component analysis. All the extracted features have shown significant discriminatory power, with particular emphasis to the RQA parameters. A decision tree classifier achieved 98.48% accuracy, 83.33% sensitivity, and 100% specificity on simulated data.Clinical Relevance-This study might guide ablation procedures, suggesting doctors to proceed directly in some patients with a pulmonary veins isolation, and avoiding the prior use of an invasive atrial mapping system.

Idioma: Inglés

DOI: 10.1109/EMBC44109.2020.9176135

Año: 2020

Publicado en: Conference proceedings (IEEE Engineering in Medicine and Biology Society. Conf.) 2020 (2020), 410-413
ISSN: 1557-170X

Financiación: info:eu-repo/grantAgreement/EC/H2020/766082/EU/MultidisciplinarY training network for ATrial fibRillation monItoring, treAtment and progression/MY-ATRIA

Tipo y forma: Artículo (PostPrint)