Metabolic syndrome before puberty: Myth or reality?

Aguilar-Gomez, F.J. ; Bueno-Lozano, G. (Universidad de Zaragoza) ; Leis, R. ; Aguilera, C.M. ; Gil-Campos, M.

Resumen: Metabolic syndrome (MetS) is defined as a cluster of alterations related with insulin resistance (obesity, dyslipidemia, hypertension, and impaired glucose metabolism), which are associated with a higher risk of cardiovascular disease in adults. Several definitions have been proposed for older children and adolescents. However, no definitions have been made in accordance with pubertal status, and those in prepubertal state have not received attention enough, despite there are data suggesting the early presence of risk factors. The new insights concerning healthy and unhealthy metabolic status or the addition of novel metabolic risk biomarkers, may contribute to the knowledge about the development of MetS in children. This manuscript reviews the available evidence on MetS during childhood, focusing on the prepubertal period.

Idioma: Inglés

DOI: 10.1016/j.coemr.2020.06.006

Año: 2020

Publicado en: Current Opinion in Endocrine and Metabolic Research 14 (2020), 97-103
ISSN: 2451-9650

Factor impacto SCIMAGO: 0.264 - Endocrinology, Diabetes and Metabolism (Q3)

Financiación: info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI051968
Financiación: info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02042
Financiación: info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-00871
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/RETICS-RD12-0026-0015

Tipo y forma: Review (PostPrint)

Área (Departamento): Área Pediatría (Dpto. Microb.Ped.Radio.Sal.Pú.)