Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Hodcroft E.B. ; Zuber M. ; Nadeau S. ; Vaughan T.G. ; Crawford K.H.D. ; Althaus C.L. ; Reichmuth M.L. ; Bowen J.E. ; Walls A.C. ; Corti D. ; Bloom J.D. ; Veesler D. ; Mateo D. ; Hernando A. ; Comas I. ; González-Candelas F. ; González-Candelas F. ; Goig G.A. ; Chiner-Oms Á. ; Cancino-Muñoz I. ; López M.G. ; Torres-Puente M. ; Gomez-Navarro I. ; Jiménez-Serrano S. ; Ruiz-Roldán L. ; Bracho M.A. ; García-González N. ; Martínez-Priego L. ; Galán-Vendrell I. ; Ruiz-Hueso P. ; De Marco G. ; Ferrús M.L. ; Carbó-Ramírez S. ; D’Auria G. ; Coscollá M. ; Ruiz-Rodríguez P. ; Roig-Sena F.J. ; Sanmartín I. ; Garcia-Souto D. ; Pequeno-Valtierra A. ; Tubio J.M.C. ; Rodríguez-Castro J. ; Rabella N. ; Navarro F. ; Miró E. ; Rodríguez-Iglesias M. ; Galán-Sanchez F. ; Rodriguez-Pallares S. ; de Toro M. ; Escudero M.B. ; Azcona-Gutiérrez J.M. ; Alberdi M.B. ; Mayor A. ; García-Basteiro A.L. ; Moncunill G. ; Dobaño C. ; Cisteró P. ; García-de-Viedma D. ; Pérez-Lago L. ; Herranz M. ; Sicilia J. ; Catalán-Alonso P. ; Muñoz P. ; Muñoz-Cuevas C. ; Rodríguez-Rodríguez G. ; Alberola-Enguidanos J. ; Nogueira J.M. ; Camarena J.J. ; Rezusta A. (Universidad de Zaragoza) ; Tristancho-Baró A. ; Milagro A. ; Martínez-Cameo N.F. ; Gracia-Grataloup Y. ; Martró E. ; Bordoy A.E. ; Not A. ; Antuori-Torres A. ; Benito R. (Universidad de Zaragoza) ; Algarate S. (Universidad de Zaragoza) ; Bueno J. ; del Pozo J.L. ; Boga J.A. ; Castelló-Abietar C. ; Rojo-Alba S. ; Alvarez-Argüelles M.E. ; Melon S. ; Aranzamendi-Zaldumbide M. ; Vergara-Gómez A. ; Fernández-Pinero J. ; Martínez M.J. ; Vila J. ; Rubio E. ; Peiró-Mestres A. ; Navero-Castillejos J. ; Posada D. ; Valverde D. ; Estévez-Gómez N. ; Fernandez-Silva I. ; de Chiara L. ; Gallego-García P. ; Varela N. ; Moreno R. ; Tirado M.D. ; Gomez-Pinedo U. ; Gozalo-Margüello M. ; Eliecer-Cano M. ; Méndez-Legaza J.M. ; Rodríguez-Lozano J. ; Siller M. ; Pablo-Marcos D. ; Oliver A. ; Reina J. ; López-Causapé C. ; Canut-Blasco A. ; Hernáez-Crespo S. ; Cordón M.L.A. ; Lecároz-Agara M.-C. ; Gómez-González C. ; Aguirre-Quiñonero A. ; López-Mirones J.I. ; Fernández-Torres M. ; Almela-Ferrer M.R. ; Gonzalo-Jiménez N. ; Ruiz-García M.M. ; Galiana A. ; Sanchez-Almendro J. ; Cilla G. ; Montes M. ; Piñeiro L. ; Sorarrain A. ; Marimón J.M. ; Gomez-Ruiz M.D. ; López-Hontangas J.L. ; González Barberá E.M. ; Navarro-Marí J.M. ; Pedrosa-Corral I. ; Sanbonmatsu-Gámez S. ; Pérez-González C. ; Chamizo-López F. ; Bordes-Benítez A. ; Navarro D. ; Albert E. ; Torres I. ; Gascón I. ; Torregrosa-Hetland C.J. ; Pastor-Boix E. ; Cascales-Ramos P. ; Fuster-Escrivá B. ; Gimeno-Cardona C. ; Ocete M.D. ; Medina-Gonzalez R. ; González-Cantó J. ; Martínez-Macias O. ; Palop-Borrás B. ; de Toro I. ; Mediavilla-Gradolph M.C. ; Pérez-Ruiz M. ; González-Recio Ó. ; Gutiérrez-Rivas M. ; Simarro-Córdoba E. ; Lozano-Serra J. ; Robles-Fonseca L. ; de Salazar A. ; Viñuela-González L. ; Chueca N. ; García F. ; Gómez-Camarasa C. ; Carvajal A. ; de la Puente R. ; Martín-Sánchez V. ; Fregeneda-Grandes J.-M. ; Molina A.J. ; Argüello H. ; Fernández-Villa T. ; Farga-Martí M.A. ; Domínguez-Márquez V. ; Costa-Alcalde J.J. ; Trastoy R. ; Barbeito-Castiñeiras G. ; Coira A. ; Pérez-del-Molino M.L. ; Aguilera A. ; Planas A.M. ; Soriano A. ; Fernandez-Cádenas I. ; Pérez-Tur J. ; Marcos M.Á. ; Moreno-Docón A. ; Viedma E. ; Mingorance J. ; Galán-Montemayor J.C. ; Parra-Grande M. ; Stadler T. ; Neher R.A.
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.
Financiación H2020 / H2020 Funds
Resumen: Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited.
Idioma: Inglés
DOI: 10.1038/s41586-021-03677-y
Año: 2021
Publicado en: Nature 595 (2021), 707-712
ISSN: 0028-0836

Factor impacto JCR: 69.504 (2021)
Categ. JCR: MULTIDISCIPLINARY SCIENCES rank: 1 / 74 = 0.014 (2021) - Q1 - T1
Factor impacto SCIMAGO: 17.897 - Multidisciplinary (Q1)

Financiación: info:eu-repo/grantAgreement/EC/H2020/101003688/EU/Epidemic intelligence to minimize 2019-nCoV’s public health, economic and social impact in Europe/EpiPose
Financiación: info:eu-repo/grantAgreement/EC/H2020/638553/EU/Integrating genomics, epidemiology and evolution to accelerate tuberculosis eradication/TB-ACCELERATE
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Microbiología (Dpto. Microb.Ped.Radio.Sal.Pú.)

Creative Commons You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.


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