Resumen: The intestine represents one of the first barriers where microorganisms and environmental antigens come into tight contact with the host immune system. A healthy intestine is essential for the well-being of humans and animals. The period after birth is a very important phase of development, as the infant moves from a protected environment in the uterus to one with many of unknown antigens and pathogens. In that period, mother’s milk plays an important role, as it contains an abundance of biologically active components. Among these components, the iron-binding glycoprotein, lactoferrin (LF), has demonstrated a variety of important benefits in infants and adults, including the promotion of intestinal health. This review article aims to provide a compilation of all the information related to LF and intestinal health, in infants and adults. Idioma: Inglés DOI: 10.3390/pharmaceutics15061569 Año: 2023 Publicado en: Pharmaceutics 15, 6 (2023), 1569 [31 pp.] ISSN: 1999-4923 Factor impacto JCR: 4.9 (2023) Categ. JCR: PHARMACOLOGY & PHARMACY rank: 45 / 354 = 0.127 (2023) - Q1 - T1 Factor impacto CITESCORE: 7.9 - Pharmaceutical Science (Q1)