Helichrysum stoechas (L.) Moench Inflorescence Extract for Tomato Disease Management

Sánchez-Hernández, Eva ; Álvarez-Martínez, Javier ; González-García, Vicente (Universidad de Zaragoza) ; Casanova-Gascón, José (Universidad de Zaragoza) ; Martín-Gil, Jesús ; Martín-Ramos, Pablo

Resumen: Helichrysum stoechas is a singular halophyte that has been shown to have anti-inflammatory, antioxidant, and allelopathic properties. In the work presented herein, we have characterized its inflorescences hydromethanolic extract and assessed its antifungal activity for the pre- and postharvest management of tomato crop diseases. Gas chromatography–mass spectrometry characterization of the extract showed that 4-ethenyl-1,3-benzenediol, 2,3-dihydro-benzofuran, quinic acid, 3,5-dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-1-benzopyran-4-one, 1,6-anhydro-β-D-glucopyranose, catechol, scopoletin, and maltol were the main constituents. The co-occurrence of pyranones, benzenediols, and quinic acids as phytoconstituents of H. stoechas extract resulted in promising in vitro minimum inhibitory concentrations of 500, 375, 500, 187.5, 187.5, and 375 μg·mL−1 against mycelia of Alternaria alternata, Colletotrichum coccodes, Fusarium oxysporum f. sp. lycopersici, Rhizoctonia solani, Sclerotinia sclerotiorum, and Verticillium dahliae, respectively. Further, to assess the potential of H. stoechas inflorescence extract for postharvest tomato crop protection, ex situ tests were conducted against C. coccodes, obtaining high protection at a dose of 750 μg·mL−1. Taking into consideration that the demonstrated activity is among the highest reported to date for plant extracts and comparable to that of the synthetic fungicides tested as positive controls, H. stoechas inflorescence extract may be put forward as a promising biorational and may deserve further testing in field-scale studies.

Idioma: Inglés

DOI: 10.3390/molecules28155861

Año: 2023

Publicado en: Molecules 28, 15 (2023), 5861 [17 pp.]
ISSN: 1420-3049

Factor impacto JCR: 4.2 (2023)

Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 77 / 231 = 0.333 (2023) - Q2 - T2
Categ. JCR: BIOCHEMISTRY & MOLECULAR BIOLOGY rank: 88 / 313 = 0.281 (2023) - Q2 - T1

Factor impacto CITESCORE: 7.4 - Pharmaceutical Science (Q1) - Analytical Chemistry (Q1) - Physical and Theoretical Chemistry (Q1) - Organic Chemistry (Q1) - Chemistry (miscellaneous) (Q1) - Drug Discovery (Q2) - Molecular Medicine (Q2)

Factor impacto SCIMAGO: 0.744 - Analytical Chemistry (Q1) - Pharmaceutical Science (Q1) - Chemistry (miscellaneous) (Q1) - Organic Chemistry (Q2) - Physical and Theoretical Chemistry (Q2) - Drug Discovery (Q2) - Medicine (miscellaneous) (Q2) - Molecular Medicine (Q3)

Financiación: info:eu-repo/grantAgreement/ES/AEI/PID2020-116055RB-C22
Financiación: info:eu-repo/grantAgreement/ES/DGA/A11-20R

Tipo y forma: Article (Published version)

Área (Departamento): Área Producción Vegetal (Dpto. CC.Agrar.y Medio Natural)
Área (Departamento): Área Botánica (Dpto. CC.Agrar.y Medio Natural)