Comorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD: The EPOC en Servicios de Medicina Interna (ESMI) Study
Almagro, Pedro ; Cabrera, Francisco Javier ; Diez Manglano, Jesús (Universidad de Zaragoza) ; Boixeda, Ramón ; Alonso Martín, Belén M. ; Murio, Cristina ; Soriano, Joan S.
Resumen: Background: Comorbidities are frequent in patients hospitalized for COPD exacerbation, but little is known about their relation with short-term mortality and hospital readmissions. Our hypothesis is that the frequency and type of comorbidities impair the prognosis within 12 weeks after discharge.
Methods: A longitudinal, observational, multicenter study of patients hospitalized for a COPD exacerbation with spirometric confirmation was performed. Comorbidity information was collected using the Charlson index and a questionnaire that included other common conditions not included in this index. Dyspnea, functional status, and previous hospitalization for COPD or other reasons among other variables were investigated. Information on mortality and readmissions for COPD or other causes was collected up to 3 months after discharge.
Results: We studied 606 patients, 594 men (89.9%), with a mean (SD) age of 72.6 (9.9) years and a postbronchodilator FEV1 of 43.2% (21.2). The mean Charlson index score was 3.1 (2.0). On admission, 63.4% of patients had arterial hypertension, 35.8% diabetes mellitus, 32.8% chronic heart failure, 20.8% ischemic heart disease, 19.3% anemia, and 34% dyslipemia. Twenty-seven patients (4.5%) died within 3 months. The Charlson index was an independent predictor of mortality (P < .003; OR,1.23; 95% CI, 1.07-1.40), even after adjustment for age, FEV1, and functional status measured with the Katz index. Comorbidity was also related with the need for hospitalization from the ED, length of stay, and hospital readmissions for COPD or other causes.
Conclusions: Comorbidities are common in patients hospitalized for a COPD exacerbation, and they are related to short-term prognosis.
Idioma: Inglés
DOI: 10.1378/chest.11-2413
Año: 2012
Publicado en: Chest 142, 5 (2012), 1126-1132
ISSN: 0012-3692
Factor impacto JCR: 5.854 (2012)
Categ. JCR: CRITICAL CARE MEDICINE rank: 3 / 26 = 0.115 (2012) - Q1 - T1
Categ. JCR: RESPIRATORY SYSTEM rank: 4 / 50 = 0.08 (2012) - Q1 - T1
Tipo y forma: Artículo (PostPrint)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
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Methods: A longitudinal, observational, multicenter study of patients hospitalized for a COPD exacerbation with spirometric confirmation was performed. Comorbidity information was collected using the Charlson index and a questionnaire that included other common conditions not included in this index. Dyspnea, functional status, and previous hospitalization for COPD or other reasons among other variables were investigated. Information on mortality and readmissions for COPD or other causes was collected up to 3 months after discharge.
Results: We studied 606 patients, 594 men (89.9%), with a mean (SD) age of 72.6 (9.9) years and a postbronchodilator FEV1 of 43.2% (21.2). The mean Charlson index score was 3.1 (2.0). On admission, 63.4% of patients had arterial hypertension, 35.8% diabetes mellitus, 32.8% chronic heart failure, 20.8% ischemic heart disease, 19.3% anemia, and 34% dyslipemia. Twenty-seven patients (4.5%) died within 3 months. The Charlson index was an independent predictor of mortality (P < .003; OR,1.23; 95% CI, 1.07-1.40), even after adjustment for age, FEV1, and functional status measured with the Katz index. Comorbidity was also related with the need for hospitalization from the ED, length of stay, and hospital readmissions for COPD or other causes.
Conclusions: Comorbidities are common in patients hospitalized for a COPD exacerbation, and they are related to short-term prognosis.
Idioma: Inglés
DOI: 10.1378/chest.11-2413
Año: 2012
Publicado en: Chest 142, 5 (2012), 1126-1132
ISSN: 0012-3692
Factor impacto JCR: 5.854 (2012)
Categ. JCR: CRITICAL CARE MEDICINE rank: 3 / 26 = 0.115 (2012) - Q1 - T1
Categ. JCR: RESPIRATORY SYSTEM rank: 4 / 50 = 0.08 (2012) - Q1 - T1
Tipo y forma: Artículo (PostPrint)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial. Si remezcla, transforma o crea a partir del material, no puede difundir el material modificado.Exportado de SIDERAL (2024-02-05-15:07:01)
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