Brief survey on organometalated antibacterial drugs and metal-based materials with antibacterial activity
Bieganski P. ; Szczupak L. ; Arruebo M. (Universidad de Zaragoza) ; Kowalski K.
Resumen: Rising bacterial antibiotic resistance is a global threat. To deal with it, new antibacterial agents and antiseptic materials need to be developed. One alternative in this quest is the organometallic derivatization of well-established antibacterial drugs and also the fabrication of advanced metal-based materials having antibacterial properties. Metal-based agents and materials often show new modes of antimicrobial action which enable them to overcome drug resistance in pathogenic bacterial strains. This review summarizes recent (2017-2020) progress in the field of organometallic-derived antibacterial drugs and metal-based materials having antibacterial activity. Specifically, it covers organometallic derivatives of antibacterial drugs including ß-lactams, ciprofloxacin, isoniazid, trimethoprim, sulfadoxine, sulfamethoxazole, and ethambutol as well as non-antibacterial drugs like metformin, phenformin and aspirin. Recent advances and reported clinical trials in the use of metal-based nanomaterials as antibiofouling coatings on medical devices, as photocatalytic agents in indoor air pollutant control, and also as photodynamic/photothermal antimicrobial agents are also summarized.
Idioma: Inglés
DOI: 10.1039/d0cb00218f
Año: 2021
Publicado en: RSC chemical biology 2, 2 (2021), 368-386
ISSN: 2633-0679
Factor impacto CITESCORE: 1.7 - Biochemistry, Genetics and Molecular Biology (Q4)
Factor impacto SCIMAGO: 0.847 - Biochemistry (Q1) - Molecular Biology (Q1) - Chemistry (miscellaneous) (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Área Ingeniería Química (Dpto. Ing.Quím.Tecnol.Med.Amb.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
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Idioma: Inglés
DOI: 10.1039/d0cb00218f
Año: 2021
Publicado en: RSC chemical biology 2, 2 (2021), 368-386
ISSN: 2633-0679
Factor impacto CITESCORE: 1.7 - Biochemistry, Genetics and Molecular Biology (Q4)
Factor impacto SCIMAGO: 0.847 - Biochemistry (Q1) - Molecular Biology (Q1) - Chemistry (miscellaneous) (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Área Ingeniería Química (Dpto. Ing.Quím.Tecnol.Med.Amb.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2025-03-19-14:19:59)
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Record created 2025-03-19, last modified 2025-03-19