Electromagnetic induction disinfection applied to cemented knee arthroplasty implants: safety evaluation of potential changes in the bone cement

Cordero García-Galán, Enrique ; Medel Rezusta, Francisco Javier (Universidad de Zaragoza) ; Sarnago, Héctor (Universidad de Zaragoza) ; Burdio, José M. (Universidad de Zaragoza) ; Lucía, Óscar (Universidad de Zaragoza) ; Esteban, Jaime ; Gómez-Barrena, Enrique

Resumen: Background: Electromagnetic induction heating is a newly developed disinfection method aimed at improving periprosthetic infection outcomes after Debridement and Implant Retention (DAIR). One safety concern is its effect over polymethylmethacrylate(PMMA). The objective of this in-vitro study is to assess such effect on cement adjacent to metallic arthroplasty components. Methods: Two different PMMA products, with and without antibiotic, were applied on three total-knee arthroplasty implants. A portable device was used to administer induction-heating protocols: 70 °C, 3.5 min and 100 °C, 3.5 min, while the third prosthesis served as control. The 602 cm−1 and 558 cm−1 bands in Raman spectroscopy were used to assess isotactic and syndiotactic components of PMMA, while 1339 cm−1, 1295 cm−1 and 882 cm−1 bands in infrared spectroscopy (ATR-FTIR) were used to assess crystallinity. Results: Isotactic/syndiotactic ratios were 0.27(±0.02) for antibiotic-free cement, and 0.41(±0.02) for gentamicin-loaded cement. After induction-heating protocols, isotactic fraction increased in antibiotic-free cement, and decreased in gentamicin-loaded cement. No evidence of crystallization was found in ATR-FTIR, except for a small increase in 1340 cm−1 band after 100 °C protocol. Conclusions: Spectroscopic techniques confirmed that PMMA only experienced minor structural changes after induction heating treatments. From a structural viewpoint, these results suggest that electromagnetic induction heating could be a safe disinfection technique for cemented implants in total knee arthroplasty

Idioma: Inglés

DOI: 10.1007/s10856-025-06870-x

Año: 2025

Publicado en: Journal of Materials Science: Materials in Medicine 36, 1 (2025), 25 pp.
ISSN: 1573-4838

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Tecnología Electrónica (Dpto. Ingeniería Electrón.Com.)
Área (Departamento): Área Ingeniería Mecánica (Dpto. Ingeniería Mecánica)