Expression of fur and its antisense anti-fur from Microcystis aeruginosa PCC 7806 as response to light and oxidative stress

Martín-Luna, Beatriz ; Sevilla, Emma ; González, Andrés (Universidad de Zaragoza) ; Bes, M. Teresa (Universidad de Zaragoza) ; Fillat, María (Universidad de Zaragoza) ; Peleato, M. Luisa (Universidad de Zaragoza)

Resumen: Ferric uptake regulation (Fur) proteins are prokaryotic transcriptional regulators that integrate signaling of iron metabolism and oxidative stress responses with several environmental stresses. In photosynthetic organisms, Fur proteins regulate many genes involved in photosynthesis, nitrogen metabolism and other key processes. Also, Fur triggers the expression of virulence factors in many bacterial pathogens, and Fur from Microcystis aeruginosa has been shown to bind promoter regions of the microcystin synthesis gene cluster. In this work, we studied transcriptional responses of fur genes under different light intensities and oxidative stress. An antisense of fur, the α-fur RNA, plays an important role in regulating fur expression under oxidative stress, affecting levels of Fur protein in cells. Importantly, an active photosynthetic electron chain is required for the expression of the fur gene.

Idioma: Inglés

Año: 2011

Publicado en: JOURNAL OF PLANT PHYSIOLOGY 168, 18 (2011), 2244-2250
ISSN: 0176-1617

Factor impacto JCR: 2.791 (2011)

Categ. JCR: PLANT SCIENCES rank: 43 / 189 = 0.228 (2011) - Q1 - T1

Tipo y forma: Article (Published version)

Área (Departamento): Área Fisiología Vegetal (Dpto. Bioq.Biolog.Mol. Celular)
Área (Departamento): Proy. investigación DEA (Dpto. Bioq.Biolog.Mol. Celular)
Área (Departamento): Área Bioquímica y Biolog.Mole. (Dpto. Bioq.Biolog.Mol. Celular)