Measles Seroprevalence Among Healthcare Professionals During a Period of Increased Transmission: A Pilot Study in Southern Italy
Anzà, Davide ; Restivo, Vincenzo ; Cirillo, Francesca ; Sasso, Bruna Lo ; Martínez-Jarreta, Begoña (Universidad de Zaragoza) ; Senia, Paola ; Vitale, Ermanno
Resumen: Objectives. Measles continues to be a significant public health concern worldwide, with suboptimal vaccination coverage (VC) contributing to periodic outbreaks, even in Europe. Despite the availability of an effective vaccine, regional disparities and declining VC, exacerbated by the COVID-19 pandemic, have increased the risk of measles transmission in Italy.
Methods. This study aimed to assess measles seroprevalence among Healthcare Professionals (HCPs) and explore associated socio-demographic factors in a country with a high level of measles circulation.
Results. Data were collected from 148 HCPs across two hospitals in Southern Italy. Serologic analyses were performed on 121 of the 148 enrolled HCPs, revealing an overall seroprevalence of 96%, however there was a substantial proportion of non-immune young female HCPs. Furthermore, smoking was significantly associated with reduced immunoglobulin levels (adjusted OR = 13.3; 95% CI= 1.07-166.2; p<0.04).
Conclusions. These findings underscore the importance of routine serological monitoring among HCPs to inform booster vaccination strategies to fill immunity gaps in high-risk groups and settings.
Idioma: Inglés
DOI: 10.1016/j.ijregi.2025.100833
Año: 2025
Publicado en: IJID regions (2025), 100833
ISSN: 2772-7076
Tipo y forma: Article (Published version)
Área (Departamento): Área Medicina Legal y Forense (Dpto. Farmac.Fisiol.y Med.L.F.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
Exportado de SIDERAL (2026-01-12-11:11:12)
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Methods. This study aimed to assess measles seroprevalence among Healthcare Professionals (HCPs) and explore associated socio-demographic factors in a country with a high level of measles circulation.
Results. Data were collected from 148 HCPs across two hospitals in Southern Italy. Serologic analyses were performed on 121 of the 148 enrolled HCPs, revealing an overall seroprevalence of 96%, however there was a substantial proportion of non-immune young female HCPs. Furthermore, smoking was significantly associated with reduced immunoglobulin levels (adjusted OR = 13.3; 95% CI= 1.07-166.2; p<0.04).
Conclusions. These findings underscore the importance of routine serological monitoring among HCPs to inform booster vaccination strategies to fill immunity gaps in high-risk groups and settings.
Idioma: Inglés
DOI: 10.1016/j.ijregi.2025.100833
Año: 2025
Publicado en: IJID regions (2025), 100833
ISSN: 2772-7076
Tipo y forma: Article (Published version)
Área (Departamento): Área Medicina Legal y Forense (Dpto. Farmac.Fisiol.y Med.L.F.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2026-01-12-11:11:12)
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Record created 2026-01-12, last modified 2026-01-12