Assessment of corneal biomechanical properties and intraocular pressure in myopic Spanish healthy population
Resumen: Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population. Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann correlated intraocular pressure (IOP), and corneal compensated IOP (IOPcc) were measured using the ocular response analyzer (ORA) in 312 eyes of 177 Spanish subjects aged between 20 and 56 years. Refraction was expressed as spherical equivalent (SE), which ranged from 0 to -16.50 diopters (D) (mean: -3.88 ± 2.90 D). Subjects were divided into four groups according to their refractive status: group 1 or control group: emmetropia (-0.50 = SE < 0.50); group 2: low myopia (-0.75 = SE < 3.00 D); group 3: moderate myopia (-3.00 = SE = -6.00D); and group 3: high myopia (SE greater than -6.00D). We analyzed the relationship between corneal biomechanicsmeasuredwithORAand SE. Results. CHin the emmetropia, lowmyopia,moderatemyopia, and highmyopia groups was 11.13 ± 0.98, 11.49 ± 1.25, 10.52 ± 1.54, and 10.35 ± 1.33mmHg, respectively. CH in the highly myopic group was significantly lower than that in the emmetropic group (¿ = 0.07) and low myopic group (¿ = 0.035); however, there were no differences with the moderate myopic group (¿ = 0.872). There were no statistically significant differences regarding IOP among the four groups (¿ > 0.05); nevertheless, IOPcc was significantly higher in the moderatelymyopic (15.47±2.47mmHg) and highlymyopic (16.14± 2.59mmHg) groups than in the emmetropia (15.15 ± 2.06mmHg) and low myopia groups (14.53 ± 2.37mmHg). No correlation between age and the measured parameters was found. CH and IOPcc were weakly but significantly correlated with SE (¿ = 0.171, ¿ = 0.002 and ¿ = -0.131, ¿ = 0.021, resp.). Conclusions. Present study showed only a very weak, but significant, correlation between CHand refractive error, with CH being lower in both moderately and highlymyopic eyes than that in the emmetropic and low myopic eyes.These changes in biomechanical properties of the cornea may have an impact on IOP measurement, increasing the risk of glaucoma
Idioma: Inglés
DOI: 10.1155/2014/905129
Año: 2014
Publicado en: Journal of Ophthalmology 2014 (2014), 905129 [6 pp.]
ISSN: 2090-004X

Factor impacto JCR: 1.425 (2014)
Categ. JCR: OPHTHALMOLOGY rank: 37 / 57 = 0.649 (2014) - Q3 - T2
Categ. JCR: MEDICINE, RESEARCH & EXPERIMENTAL rank: 92 / 123 = 0.748 (2014) - Q3 - T3

Tipo y forma: Artículo (Versión definitiva)
Área (Departamento): Oftalmología (Departamento de Cirugía, Ginecología y Obstetricia)
Área (Departamento): Mec. de Medios Contínuos y Teor. de Estructuras (Departamento de Ingeniería Mecánica)


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Exportado de SIDERAL (2017-05-04-09:41:37)

Este artículo se encuentra en las siguientes colecciones:
Artículos > Artículos por área > Mec. de Medios Contínuos y Teor. de Estructuras
Artículos > Artículos por área > Oftalmología



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